alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride
- Product Name
- alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride
- CAS No.
- 326-43-2
- Chemical Name
- alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride
- Synonyms
- Vazalmin;Firmalgil;Phenyramidol HCl;FENYRAMIDOLHYDROCHLORIDE;1-Phenyl-2-(pyridin-2-ylamino)ethanol hydrochloride;alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride;Benzenemethanol, a-[(2-pyridinylamino)methyl]-,hydrochloride (1:1)
- CBNumber
- CB1906929
- Molecular Formula
- C13H15ClN2O
- Formula Weight
- 250.724
- MOL File
- 326-43-2.mol
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Property
- Melting point:
- 140-142°
Safety
- Toxicity
- LD50 oral in mouse: 2425mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0016333
- Product name
- PHENYRAMIDOL HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.22
- Updated
- 2021/12/16
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Chemical Properties,Usage,Production
Originator
Analexin, Mallinckrodt Inc., US ,1960
Uses
Analgesic; relaxant (skeletal muscle).
Manufacturing Process
A mixture containing 188 g (0.20 mol) of 2-arninopyridine, 0.55 g of lithium amide and 75 cc of anhydrous toluene was refluxed for 1.5 hours. Styrene oxide (12.0 g = 0.10 mol) was then added to the reaction mixture with stirring over a period of ten minutes. The reaction mixture was stirred and refluxed for an additional 3.5 hours. A crystalline precipitate was formed during the reaction which was removed by filtration, MP 170°C to 171°C. 1.5 g. The filtrate was concentrated to dryness and a dark residue remained which was crystallized from anhydrous ether; yield 6.0 g. Upon recrystallization of the crude solid from 30 cc of isopropyl alcohol, 2.0 g of a light yellow solid was isolated; MP 170° to 171°C.
Therapeutic Function
Analgesic, Muscle relaxant
alpha-[(2-pyridylamino)methyl]benzyl alcohol monohydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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