ChemicalBook > CAS DataBase List > (S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione

Product Name
(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
CAS No.
51372-28-2
Chemical Name
(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
Synonyms
S-22Budesonide;Budesonide-22S;(22S)-Budesonide;Budenoside Impurity 3;Budesonide (22S)-Isomer;Budesonide USP Impurity C(S);(22S)-Budesonide (85:15 = S:R);Budesonide Impurity 25 ((22S)-Budesonide);(S)-16α,17-(butylidenedioxy)-11β,21-dihydroxypregna-1,4-diene-3,20-dione;16α,17-[(S)-Butylidenebisoxy]-11β,21-dihydroxypregna-1,4-diene-3,20-dione
CBNumber
CB1929885
Molecular Formula
C25H34O6
Formula Weight
430.53
MOL File
51372-28-2.mol
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(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione Property

Melting point:
196-198°C
Boiling point:
599.7±50.0 °C(Predicted)
Density 
1.27±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), Dichloromethane, Methanol (Slightly)
form 
Solid
pka
12.87±0.10(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B689505
Product name
(22S)-Budesonide
Packaging
5mg
Price
$95
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19348
Product name
(22S)-Budesonide
Packaging
1mg
Price
$465
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010363
Product name
BUDESONIDE-22S
Purity
95.00%
Packaging
0.5MG
Price
$642.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB19348
Product name
(22S)-Budesonide
Packaging
2mg
Price
$840
Updated
2021/12/16
AK Scientific
Product number
3996EB
Product name
(1S,2S,6S,8S,9S,11S,12S,13R)-11-Hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-6-propyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
Packaging
2mg
Price
$1184
Updated
2021/12/16
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(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

Budesonide (B689490) epimer S. Budesonide 22R epimer is more active than 22S epimer.

brand name

Entocort (AstraZeneca); Pulmicort (AstraZeneca); Rhinocort (AstraZeneca).

(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione Suppliers

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51372-28-2, (S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dioneRelated Search:


  • (S)-16alpha,17-(butylidenedioxy)-11beta,21-dihydroxypregna-1,4-diene-3,20-dione
  • Budesonide-22S
  • S-22Budesonide
  • (22S)-Budesonide
  • 16α,17-[(S)-Butylidenebisoxy]-11β,21-dihydroxypregna-1,4-diene-3,20-dione
  • (22S)-Budesonide (85:15 = S:R)
  • Budesonide (22S)-Isomer
  • Budenoside Impurity 3
  • Pregna-1,4-diene-3,20-dione, 16,17-[(1S)-butylidenebis(oxy)]-11,21-dihydroxy-, (11β,16α)-
  • Budesonide Impurity 25 ((22S)-Budesonide)
  • (6aR,6bS,7S,8aS,8bS,10S,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a-dimethyl-10-propyl-1,2,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-4H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4-one
  • (S)-16α,17-(butylidenedioxy)-11β,21-dihydroxypregna-1,4-diene-3,20-dione
  • Budesonide USP Impurity C(S)
  • 51372-28-2
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids