Sinomenine N-oxide

Product Name: Sinomenine N-oxide
CAS No.: 1000026-77-6
Chemical Name: Sinomenine N-oxide
Synonyms: Sinomenine N-oxide;Sinomenine N-oxide, 10 mM in DMSO;Sinomenine N oxide,Sinomenine Noxide;Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide,;Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide, (9α,13α,14α)-
CBNumber: CB19308106
Molecular Formula: C19H23NO5
Formula Weight: 345.4
MOL File: 1000026-77-6.mol

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Sinomenine N-oxide Property

Melting point:: 155-156 °C(Solv: methanol (67-56-1))
pka: 9.24±0.40(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Sinomenine N-oxide Chemical Properties,Usage,Production

Description

Sinomenine N-oxide is a plant extract with anti-angiogenic, anti-inflammatory and anti-rheumatic properties. It is also an inhibitor of NO production with an IC50 value of 23.04 μM.

Uses

Sinomenine N-oxide has anti-angiogenic, anti-inflammatory and anti-rheumatic effects. Sinomenine N-oxide is also a NO production inhibitor, with an IC50 value of 23.04 μM[1][2][3].

References

[1] Liu WJ, et al. Network pharmacology approach to elucidate possible action mechanisms of Sinomenii Caulis for treating osteoporosis. J Ethnopharmacol. 2020 Jul 15;257:112871. DOI:10.1016/j.jep.2020.112871
[2] Zeng HL, et al. New N-oxide alkaloids from the stems of Sinomenium acutum. Fitoterapia. 2023 Mar;165:105404. DOI:10.1016/j.fitote.2022.105404
[3] Li Q, et al. Metabolic mechanism and anti-inflammation effects of sinomenine and its major metabolites N-demethylsinomenine and sinomenine-N-oxide. Life Sci. 2020 Nov 15;261:118433. DOI:10.1016/j.lfs.2020.118433

Sinomenine N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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Sinomenine N-oxide Suppliers

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1000026-77-6, Sinomenine N-oxideRelated Search:

Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide, (9α,13α,14α)-

Morphinan-6-one, 7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-, 17-oxide,

Sinomenine N oxide,Sinomenine Noxide

Sinomenine N-oxide, 10 mM in DMSO

Sinomenine N-oxide

1000026-77-6

10000026-77-6