3-Bromo-L-tyrosine
- Product Name
- 3-Bromo-L-tyrosine
- CAS No.
- 38739-13-8
- Chemical Name
- 3-Bromo-L-tyrosine
- Synonyms
- H-Tyr(3-Br)-OH;L-3-Bromotyrosine;3-Bromo-L-tyrosine;L-Tyrosine, 3-bromo-;3-bromo-L-tyrosine (L-type);(S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid;(2S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid
- CBNumber
- CB1966684
- Molecular Formula
- C9H10BrNO3
- Formula Weight
- 260.08
- MOL File
- 38739-13-8.mol
3-Bromo-L-tyrosine Property
- Melting point:
- 247-248 °C
- Boiling point:
- 402.8±45.0 °C(Predicted)
- Density
- 1.710±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Aqueous Acid (Sparingly), DMSO (Heated), Methanol (Heated)
- form
- Solid
- pka
- 2.21±0.20(Predicted)
- color
- White to Pale Brown
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B688565
- Product name
- 3-Bromo-L-tyrosine
- Packaging
- 1g
- Price
- $175
- Updated
- 2021/12/16
- Product number
- AS40828
- Product name
- (S)-2-Amino-3-(3-bromo-4-hydroxyphenyl)propanoic acid
- Purity
- 97% ee
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- CS-W019172
- Product name
- 3-Bromo-L-tyrosine
- Purity
- 98.33%
- Packaging
- 5g
- Price
- $94
- Updated
- 2021/12/16
- Product number
- CS-W019172
- Product name
- 3-Bromo-L-tyrosine
- Purity
- 98.33%
- Packaging
- 10g
- Price
- $132
- Updated
- 2021/12/16
- Product number
- 5012AB
- Product name
- 3-Bromo-L-tyrosine
- Packaging
- 10g
- Price
- $222
- Updated
- 2021/12/16
3-Bromo-L-tyrosine Chemical Properties,Usage,Production
Uses
3-Bromo-L-tyrosine is used in the preparation and synthesis of polyclonal antibodies that work against brominated protein related allergic responses and afflictions. Also effective in asthma control a nd prediction in children.
Definition
ChEBI: 3-bromo-L-tyrosine is a bromoamino acid comprising an L-tyrosine core with a bromo- substituent ortho to the hydroxy group on the benzene ring. It is a bromoamino acid, a L-tyrosine derivative, a member of bromobenzenes and a non-proteinogenic L-alpha-amino acid. It is a tautomer of a 3-bromo-L-tyrosine zwitterion.
Synthesis
60-18-4
38739-13-8
The general procedure for the synthesis of (S)-2-amino-3-(3-bromo-4-hydroxyphenyl)propionic acid from L-tyrosine was as follows: reaction of D- or L-tyrosine (1.0 g) with N-bromosuccinimide (NBS, 1.5 g, 8.3 mmol) in anhydrous THF (15 mL). The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the solution was concentrated under reduced pressure and purified by rapid column chromatography on silica gel to afford D- or L-3-bromotyrosine (100 mg). The product was analyzed by electrospray mass spectrometry (positive ion mode) and showed m/z 260/262 (1:1).1H NMR (500 MHz, CD3OD) data were as follows: δH 7.46 (s, H-2); 7.13 (d, J = 8.2 Hz, H-6); 6.91 (d, J = 8.2 Hz, H-5); 3.97 (m, H-8); 3.22 (dd, J = 4.6, 14.6 Hz, H-7a); 3.03 (dd, J = 7.8, 14.6 Hz, H-7b).
References
[1] Amino Acids, 2013, vol. 44, # 2, p. 529 - 532
[2] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[3] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[4] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1925, vol. 144, p. 250
[5] Patent: US2007/259883, 2007, A1. Location in patent: Page/Page column 8
3-Bromo-L-tyrosine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Bromo-L-tyrosine manufacturers
- Product
- 3-Bromo-L-tyrosine 38739-13-8
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg -1000kg
- Release date
- 2020-01-02