2-Cyanothiazole
- Product Name
- 2-Cyanothiazole
- CAS No.
- 1452-16-0
- Chemical Name
- 2-Cyanothiazole
- Synonyms
- 2-Cyanothiazole;2-Cyanothiazole,95%;Thiazol-2-carbonitril;2-Thiazolecarbonitrile;Thiazol-2-carbonitrile;1,3-thiazole-2-carbonitrile cz;2-Cyanothiazole thiazole-2-carbonitrile
- CBNumber
- CB1967353
- Molecular Formula
- C4H2N2S
- Formula Weight
- 110.14
- MOL File
- 1452-16-0.mol
2-Cyanothiazole Property
- Boiling point:
- 203℃
- Density
- 1.33
- Flash point:
- 76℃
- storage temp.
- 2-8°C
- form
- Solid
- pka
- -1.13±0.10(Predicted)
- Appearance
- Light brown to brown Oil
- Water Solubility
- Slightly soluble in water.
- InChI
- InChI=1S/C4H2N2S/c5-3-4-6-1-2-7-4/h1-2H
- InChIKey
- ZIRGWUZHKJDYKT-UHFFFAOYSA-N
- SMILES
- S1C=CN=C1C#N
- CAS DataBase Reference
- 1452-16-0
Safety
- RIDADR
- 3439
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2934100090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H371May cause damage to organs
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C982305
- Product name
- 2-Cyanothiazole
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- P000114316
- Product name
- 2-Cyanothiazole
- Purity
- 98%
- Packaging
- 250mg
- Price
- $12
- Updated
- 2021/12/16
- Product number
- P000114316
- Product name
- 2-Cyanothiazole
- Purity
- 98%
- Packaging
- 1g
- Price
- $29
- Updated
- 2021/12/16
- Product number
- 072294
- Product name
- 2-Cyanothiazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- P000114316
- Product name
- 2-Cyanothiazole
- Purity
- 98%
- Packaging
- 5g
- Price
- $88
- Updated
- 2021/12/16
2-Cyanothiazole Chemical Properties,Usage,Production
Uses
2-Cyanothiazole is used as a intermediate for pharmaceutical and chemical research.
Synthesis
10200-59-6
1452-16-0
GENERAL METHOD: 2-formylthiazole (54 mg, 0.5 mmol) and ammonium acetate (385 mg, 5.0 mmol) were dissolved in acetonitrile (6 mL) at room temperature, followed by the addition of trimethylphenyltrimethylammonium (376 mg, 1.0 mmol). The reaction mixture was stirred at room temperature for 21 h. The reaction mixture was sequentially treated with 0.5 M Na2S2O3 aqueous solution (10 mL) and 1.0 M NaHCO3 aqueous solution (15 mL), and then extracted with ethyl acetate (60 mL). The organic layer was washed sequentially with 0.5 M Na2S2O3 aqueous solution and saturated NaCl aqueous solution, and finally dried with anhydrous MgSO4.
References
[1] Heterocycles, 2016, vol. 92, # 10, p. 1796 - 1802
[2] Patent: EP1555257, 2005, A1. Location in patent: Page/Page column 25
[3] Tetrahedron Letters, 2013, vol. 54, # 17, p. 2177 - 2179
[4] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 3, p. 496 - 500
2-Cyanothiazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Cyanothiazole manufacturers
- Product
- 2-Cyanothiazole 1452-16-0
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-12
- Product
- 2-Cyanothiazole 1452-16-0
- Price
- US $500.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2018-08-04