ChemicalBook > CAS DataBase List > N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine

N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine

Product Name
N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine
CAS No.
152918-26-8
Chemical Name
N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine
Synonyms
ABMECA,AB MECA;AB-MECA HIGH AFFINITY A3 ADEN;N6-(4-AMINOBENZYL)-N-METHYLCARBOXAMIDOADENOSINE;n6-(4-aminobenzyl)-9-[5-(methylcarbonyl)-β-d-ribofuranosyl]adenine;β-D-Ribofuranuronamide, 1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-;N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine, N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β-D-ribofuranosyl]adenine
CBNumber
CB1973000
Molecular Formula
C18H21N7O4
Formula Weight
399.4
MOL File
152918-26-8.mol
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N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Property

Density 
1.68±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble0.3mg/mL
pka
12.72±0.70(Predicted)
form 
solid
color 
off-white
Water Solubility 
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.3mg/mL
ethanol: 1mg/mL
DMSO: 10mg/mL
dilute aqueous base: 3.5mg/mL
H2O: insoluble
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A236
Product name
AB-MECA
Purity
solid
Packaging
1mg
Price
$131
Updated
2025/07/31
Sigma-Aldrich
Product number
A236
Product name
AB-MECA
Purity
solid
Packaging
5mg
Price
$330
Updated
2025/07/31
Cayman Chemical
Product number
28415
Product name
AB-MECA
Packaging
1mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
28415
Product name
AB-MECA
Packaging
10mg
Price
$575
Updated
2024/03/01
Cayman Chemical
Product number
28415
Product name
AB-MECA
Packaging
5mg
Price
$324
Updated
2024/03/01
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N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Chemical Properties,Usage,Production

Uses

AB-MECA is a high affinity A3 adenosine receptor agonist.

Biochem/physiol Actions

High affinity A3 adenosine receptor agonist.

in vivo

AB-MECA (3 ug/kg; iv) enhances plasma histamine level in mouse[4].
AB-MECA (0.3 mg/kg; iv) enhances antigen-induced bronchoconstriction in male albino guinea pigs, weighing 180-220 g[5].

Animal Model:Male Balb/c mice, weighing 18-25 g[4]
Dosage:3 ug/kg
Administration:IV; single dose
Result:Induced a 5.9-fold increase in histamine levels in murine plasma.

IC 50

Adenosine A3 receptor

N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine Suppliers

China 26 South Korea 1 Switzerland 1 United States 8 Global 36
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Switzerland
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152918-26-8, N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosineRelated Search:


  • AB-MECA HIGH AFFINITY A3 ADEN
  • n6-(4-aminobenzyl)-9-[5-(methylcarbonyl)-β-d-ribofuranosyl]adenine
  • N6-(4-Aminobenzyl)-N-methylcarboxamidoadenosine, N6-(4-Aminobenzyl)-9-[5-(methylcarbonyl)-β-D-ribofuranosyl]adenine
  • β-D-Ribofuranuronamide, 1-[6-[[(4-aminophenyl)methyl]amino]-9H-purin-9-yl]-1-deoxy-N-methyl-
  • N6-(4-AMINOBENZYL)-N-METHYLCARBOXAMIDOADENOSINE
  • ABMECA,AB MECA
  • 152918-26-8