3-ACETOXY-5-BROMOINDOLE
- Product Name
- 3-ACETOXY-5-BROMOINDOLE
- CAS No.
- 17357-14-1
- Chemical Name
- 3-ACETOXY-5-BROMOINDOLE
- Synonyms
- 5-BROMOINDOXYL ACETATE;5-BROMOINDOLYL ACETATE;O-ACETYL-5-BROMOINDOXYL;3-ACETOXY-5-BROMOINDOLE;5-BROMOINDOXYL-3-ACETATE;5-BROMOINDOLYL 3-ACETATE;5-Bromo-3-indoxylacetate;5-Bromo-3-indolyl Acetate;5-Bromoindoxyl acetate,98%;5-Bromoindoxyl Acetate >
- CBNumber
- CB2103635
- Molecular Formula
- C10H8BrNO2
- Formula Weight
- 254.08
- MOL File
- 17357-14-1.mol
3-ACETOXY-5-BROMOINDOLE Property
- Melting point:
- 130-132 °C(lit.)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- ethanol: soluble50mg/mL, clear, colorless
- form
- powder to crystal
- color
- White to Purple
- BRN
- 168698
- InChI
- 1S/C10H8BrNO2/c1-6(13)14-10-5-12-9-3-2-7(11)4-8(9)10/h2-5,12H,1H3
- InChIKey
- KFTGECHXNQBTNZ-UHFFFAOYSA-N
- SMILES
- CC(=O)Oc1c[nH]c2ccc(Br)cc12
- CAS DataBase Reference
- 17357-14-1(CAS DataBase Reference)
- EPA Substance Registry System
- 1H-Indol-3-ol, 5-bromo-, acetate (ester) (17357-14-1)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 374210
- Product name
- 5-Bromoindoxyl acetate
- Purity
- 98%
- Packaging
- 1g
- Price
- $365
- Updated
- 2025/07/31
- Product number
- A0940
- Product name
- 5-Bromoindoxyl Acetate
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 100mg
- Price
- $35
- Updated
- 2025/07/31
- Product number
- FA52314
- Product name
- 3-Acetoxy-5-bromoindole
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 5823AF
- Product name
- 3-Acetoxy-5-bromoindole
- Packaging
- 100mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- FA52314
- Product name
- 3-Acetoxy-5-bromoindole
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
3-ACETOXY-5-BROMOINDOLE Chemical Properties,Usage,Production
Uses
5-Bromoindoxyl acetate may be used:
- as esterase substrate to investigate the activity of non-specific esterase in the matrix of developing bovine enamel
- in histochemical studies of the nonspecific esterase of mouse epididymis
- as substrate to investigate the esterase activity in guinea-pig thyroid and mouse epididymis epithelial cells
- in staining procedure for the frozen sections of muscle fixed in buffered formaldehyde
General Description
5-Bromoindoxyl acetate is a halogenated heterocyclic compound. It is widely used as esterase substrate.
Synthesis
Method I.
The 3-hydroxyindole acetate, N-bromosuccinimide and 150 mL of carbon tetrachloride. It was added into 250 mL round bottom flask and refluxed in oil bath for 2 h. The reaction process was monitored by TLC. At the completion of the reaction, the solution changed from dark yellow to light yellow and a white solid (succinimide) was precipitated. The filtrate was withdrawn and washed, and the filtrate was collected and evaporated to obtain 5-bromo-3-hydroxyindole acetate.
Method II.
In a 500 mL single-necked flask, 3-hydroxyindole acetic acid ester was dissolved in tetrahydrofuran solution, N-bromosuccinimide was added in an ice bath, and the reaction was stirred at 0??C for 3 h. The reaction was completed. The reaction mixture was poured into 150 mL of ice water and extracted with methyl tert-butyl ether (100 mL??4), the organic phases were combined, dried with anhydrous sodium sulfate, and concentrated to obtain 5-bromo-3-hydroxyindole acetate.
3-ACETOXY-5-BROMOINDOLE Preparation Products And Raw materials
Raw materials
Preparation Products
3-ACETOXY-5-BROMOINDOLE Suppliers
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View Lastest Price from 3-ACETOXY-5-BROMOINDOLE manufacturers
- Product
- 3-ACETOXY-5-BROMOINDOLE 17357-14-1
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100KG
- Release date
- 2020-01-30