2-AMINO-5-FLUOROBENZOTHIAZOLE

Product Name: 2-AMINO-5-FLUOROBENZOTHIAZOLE
CAS No.: 20358-07-0
Chemical Name: 2-AMINO-5-FLUOROBENZOTHIAZOLE
Synonyms: 5-FLUOROBENZO[D]THIAZOL-2-AMINE;5-Fluoro-2-benzothiazolamine;2-BenzothiazolaMine,5-fluoro-;2-AMino-5-fluorobenzothiozole;2-AMINO-5-FLUOROBENZOTHIAZOLE;5-Fluoro-2-benzo[d]thiazolamine;2-Amino-5-fluorobenzothiazole>(5-Fluorobenzothiazol-2-yl)amine;5-fluoro-1,3-benzothiazol-2-amine;2-Benzothiazolamine,5-fluoro-(9CI)
CBNumber: CB2107244
Molecular Formula: C7H5FN2S
Formula Weight: 168.19
MOL File: 20358-07-0.mol

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2-AMINO-5-FLUOROBENZOTHIAZOLE Property

Melting point:: 181°C
Boiling point:: 312.0±34.0 °C(Predicted)
Density: 1.491
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in methanol.
pka: 3.81±0.10(Predicted)
Appearance: Off-white to light brown Solid
CAS DataBase Reference: 20358-07-0

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Safety

Risk Statements: 36/37/38-36/38
Safety Statements: 26-36/37/39-28
HS Code: 29342000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2682
Product name: 2-Amino-5-fluorobenzothiazole
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $82
Updated: 2025/07/31

TCI Chemical

Product number: A2682
Product name: 2-Amino-5-fluorobenzothiazole
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $247
Updated: 2025/07/31

TRC

Product number: A576928
Product name: 2-Amino-5-fluorobenzothiazole
Packaging: 50mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA33580
Product name: 2-Amino-5-fluorobenzothiazole
Packaging: 2g
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA33580
Product name: 2-Amino-5-fluorobenzothiazole
Packaging: 5G
Price: $125
Updated: 2021/12/16

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2-AMINO-5-FLUOROBENZOTHIAZOLE Chemical Properties,Usage,Production

Chemical Properties

Powder

Uses

2-Amino-5-fluorobenzothiazole is used as organic chemical synthesis intermediate.

Synthesis

458-05-9

20358-07-0

General procedure for the synthesis of 5-fluoro-2-aminobenzothiazole from 1-(3-fluorophenyl)-2-thiourea: 1-(3-fluorophenyl)-2-thiourea (270 mg, 1.59 mmol) was dissolved in dichloromethane (3 mL) at 0 °C. A solution of bromine (279 mg, 1.74 mmol) in dichloromethane (1 mL) was slowly added dropwise for 30 min at 10 °C or lower. Subsequently, the reaction mixture was refluxed for 3 hours. After completion of the reaction, the organic layer was dried with anhydrous magnesium sulfate, filtered and the filtrate was concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: dichloromethane/petroleum ether = 1:1) and dried with anhydrous magnesium sulfate to give the final 5-fluoro-2-aminobenzothiazole (183 mg, 68% yield).

References

[1] Patent: KR101659952, 2016, B1. Location in patent: Paragraph 0247; 0248; 0252
[2] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 24, p. 8599 - 8607
[3] Journal of the Chemical Society [Section] C: Organic, 1969, p. 268 - 272
[4] Patent: US5356864, 1994, A
[5] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00212

2-AMINO-5-FLUOROBENZOTHIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-FLUOROBENZOTHIAZOLE Suppliers

Americas 1 China 138 Europe 2 Germany 1 India 8 Japan 1 Poland 1 Switzerland 1 The Netherlands 1 United Kingdom 7 United States 14 Global 175

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View Lastest Price from 2-AMINO-5-FLUOROBENZOTHIAZOLE manufacturers

Career Henan Chemical Co

Product: 2-AMINO-5-FLUOROBENZOTHIAZOLE 20358-07-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-24

20358-07-0, 2-AMINO-5-FLUOROBENZOTHIAZOLERelated Search:

2-AMINO-5-FLUOROBENZOTHIAZOLE 2-AMINO-4-FLUOROBENZOTHIAZOLE 2-AMINO-6-FLUOROBENZOTHIAZOLE 2-AMINO-5,6-DIFLUOROBENZOTHIAZOLE 2-Amino-6-bromo-5,7-difluorobenzothiazole 2-Amino-5,6,7-trifluorobenzotriazole 4,5-DIFLUORO-2-BENZOTHIAZOLEHYDRAZINE 5,7-DIFLUORO-1,3-BENZOTHIAZOL-2-AMINE 5-FLUOROBENZOTHIAZOLE 2-CHLORO-N-(4,5,6-TRIFLUORO-BENZOTHIAZOL-2-YL)-ACETAMIDE 2-CHLORO-N-(5-FLUORO-1,3-BENZOTHIAZOL-2-YL)ACETAMIDE N1-(5,7-DIFLUORO-1,3-BENZOTHIAZOL-2-YL)-2-BROMOACETAMIDE 2-HYDROXY-N-(4,5,6-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)ACETAMIDE 2-AMINO-5-FLUORO-6-METHYLBENZOTHIAZOLE N-(5-fluorobenzothiazol-2-yl)-2-guanidinothiazole-4-carboxamide 4,5,6-TRIFLUORO-BENZOTHIAZOL-2-YLAMINE 5,7-DIFLUORO-2-BENZOTHIAZOLEHYDRAZINE N1-(5-FLUORO-1,3-BENZOTHIAZOL-2-YL)-2-BROMOACETAMIDE

2-AMINO-5-FLUOROBENZOTHIAZOLE

5-FLUORO-1,3-BENZOTHIAZOL-2-YLAMINE

5-FLUOROBENZO[D]THIAZOL-2-AMINE

2-Benzothiazolamine,5-fluoro-(9CI)

5-fluoro-1,3-benzothiazol-2-amine

2-BenzothiazolaMine,5-fluoro-

(5-Fluorobenzothiazol-2-yl)amine

2-AMino-5-fluorobenzothiozole

5-Fluoro-2-benzo[d]thiazolamine

2-Amino-5-fluorobenzothiazole&gt

Cyclopropanamine,1-ethyl-,hydrochloride(1:6)

5-Fluoro-2-benzothiazolamine

20358-07-0

BENZOTHIAZOLE

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