ChemicalBook > CAS DataBase List > [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)

[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)

Product Name
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
CAS No.
614750-81-1
Chemical Name
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
Synonyms
CPD3325-A3;WXHL-012 S4;6-Formyl-1,2,4-triazolo[1,5-a]pyridine;[1,2,4]triazolo[1,5-a]pyridine-6-carbaldehyde;1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBOXALDEHYDE;1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde 97%;1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde;[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI);6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine
CBNumber
CB21089495
Molecular Formula
C7H5N3O
Formula Weight
147.13
MOL File
614750-81-1.mol
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[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Property

Melting point:
156-158
Density 
1.39±0.1 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
solid
pka
1.57±0.30(Predicted)
Appearance
Light yellow to yellow Solid
InChIKey
SYLGZKAGHAOGFM-UHFFFAOYSA-N
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Safety

WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
760323
Product name
1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde
Purity
97%
Packaging
500mg
Price
$103
Updated
2023/06/20
ChemScene
Product number
CS-W018214
Product name
[1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde
Purity
>97.0%
Packaging
250mg
Price
$115
Updated
2021/12/16
AK Scientific
Product number
X6634
Product name
1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde
Packaging
250mg
Price
$208
Updated
2021/12/16
Matrix Scientific
Product number
081746
Product name
[1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde
Purity
95%
Packaging
1g
Price
$488
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0097155
Product name
[1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBALDEHYDE
Purity
95.00%
Packaging
5MG
Price
$501.75
Updated
2021/12/16
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[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Chemical Properties,Usage,Production

Synthesis

68-12-2

614750-81-1

General procedure for the synthesis of [1,2,4]triazolo[1,5-a]pyridine-6-carbaldehyde from N,N-dimethylformamide: (a) A solution of 6-iodo-[1,2,4]triazolo[1,5-a]pyridine (5.0 g) was prepared by dissolving 2-amino-5-iodopyridine (20 mmol) in anhydrous THF (300 mL) at 0 °C and slowly adding THF solution of isopropylmagnesium bromide (1M, 31 mL, 31 mmol). The resulting emulsion suspension was stirred at 0 °C for 1 h. DMF (6 mL, 50 mmol) was added. The suspension was allowed to warm up to room temperature and stirring was continued for 4 hours. Subsequently, 100 mL of water was added at room temperature and stirred for 1 hour. The reaction mixture was extracted with diethyl ether and washed with saturated Na2CO3 solution. The organic phase was dried with MgSO4 and concentrated. The residue was purified by silica gel short column chromatography using EtOAc as eluent to afford [1,2,4]triazolo[1,5-a]pyridine-6-carboxaldehyde as a light yellow solid (3 g, 100% yield). ESI-MS m/z: 148.0 [M+H]+. 1H NMR (CDCl3, 300MHz) δ: 10.03 (s, 1H), 9.10 (s, 1H), 8.49 (s, 1H), 8.02 (d, 1H), 7.82 (d, 1H).

References

[1] Patent: US2006/63809, 2006, A1. Location in patent: Page/Page column 17

[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

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[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Suppliers

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View Lastest Price from [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) manufacturers

Career Henan Chemical Co
Product
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) 614750-81-1
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-08
Career Henan Chemical Co
Product
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) 614750-81-1
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08