[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
- Product Name
- [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
- CAS No.
- 614750-81-1
- Chemical Name
- [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI)
- Synonyms
- CPD3325-A3;WXHL-012 S4;6-Formyl-1,2,4-triazolo[1,5-a]pyridine;[1,2,4]triazolo[1,5-a]pyridine-6-carbaldehyde;1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBOXALDEHYDE;1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde 97%;1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde;[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI);6-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine
- CBNumber
- CB21089495
- Molecular Formula
- C7H5N3O
- Formula Weight
- 147.13
- MOL File
- 614750-81-1.mol
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Property
- Melting point:
- 156-158
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- 1.57±0.30(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChIKey
- SYLGZKAGHAOGFM-UHFFFAOYSA-N
Safety
- WGK Germany
- 3
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 760323
- Product name
- 1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde
- Purity
- 97%
- Packaging
- 500mg
- Price
- $103
- Updated
- 2023/06/20
- Product number
- CS-W018214
- Product name
- [1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde
- Purity
- >97.0%
- Packaging
- 250mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- X6634
- Product name
- 1,2,4-Triazolo[1,5-a]pyridine-6-carboxaldehyde
- Packaging
- 250mg
- Price
- $208
- Updated
- 2021/12/16
- Product number
- 081746
- Product name
- [1,2,4]Triazolo[1,5-a]pyridine-6-carbaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $488
- Updated
- 2021/12/16
- Product number
- CHM0097155
- Product name
- [1,2,4]TRIAZOLO[1,5-A]PYRIDINE-6-CARBALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.75
- Updated
- 2021/12/16
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Chemical Properties,Usage,Production
Synthesis
68-12-2
614750-81-1
General procedure for the synthesis of [1,2,4]triazolo[1,5-a]pyridine-6-carbaldehyde from N,N-dimethylformamide: (a) A solution of 6-iodo-[1,2,4]triazolo[1,5-a]pyridine (5.0 g) was prepared by dissolving 2-amino-5-iodopyridine (20 mmol) in anhydrous THF (300 mL) at 0 °C and slowly adding THF solution of isopropylmagnesium bromide (1M, 31 mL, 31 mmol). The resulting emulsion suspension was stirred at 0 °C for 1 h. DMF (6 mL, 50 mmol) was added. The suspension was allowed to warm up to room temperature and stirring was continued for 4 hours. Subsequently, 100 mL of water was added at room temperature and stirred for 1 hour. The reaction mixture was extracted with diethyl ether and washed with saturated Na2CO3 solution. The organic phase was dried with MgSO4 and concentrated. The residue was purified by silica gel short column chromatography using EtOAc as eluent to afford [1,2,4]triazolo[1,5-a]pyridine-6-carboxaldehyde as a light yellow solid (3 g, 100% yield). ESI-MS m/z: 148.0 [M+H]+. 1H NMR (CDCl3, 300MHz) δ: 10.03 (s, 1H), 9.10 (s, 1H), 8.49 (s, 1H), 8.02 (d, 1H), 7.82 (d, 1H).
References
[1] Patent: US2006/63809, 2006, A1. Location in patent: Page/Page column 17
[1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) Preparation Products And Raw materials
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View Lastest Price from [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) manufacturers
- Product
- [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) 614750-81-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-08
- Product
- [1,2,4]Triazolo[1,5-a]pyridine-6-carboxaldehyde (9CI) 614750-81-1
- Price
- US $6.68/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2020-01-08