ChemicalBook > CAS DataBase List > 2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID

2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID

Product Name
2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID
CAS No.
1003709-39-4
Chemical Name
2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID
Synonyms
2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID;Benzoic acid, 2-bromo-4-fluoro-5-methyl-
CBNumber
CB21090905
Molecular Formula
C8H6BrFO2
Formula Weight
233.03
MOL File
Mol file
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2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID Property

Boiling point:
309.0±42.0 °C(Predicted)
Density 
1.680±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.86±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AK Scientific
Product number
X4311
Product name
2-bromo-4-fluoro-5-methylbenzoicacid
Packaging
250mg
Price
$107
Updated
2021/12/16
Apolloscientific
Product number
PC201001
Product name
2-Bromo-4-fluoro-5-methylbenzoic acid
Packaging
1g
Price
$154
Updated
2021/12/16
Apolloscientific
Product number
PC201001
Product name
2-Bromo-4-fluoro-5-methylbenzoic acid
Packaging
5g
Price
$459
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0065954
Product name
2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID
Purity
95.00%
Packaging
5MG
Price
$503.54
Updated
2021/12/16
Apolloscientific
Product number
PC201001
Product name
2-Bromo-4-fluoro-5-methylbenzoic acid
Packaging
10g
Price
$751
Updated
2021/12/16
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2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

916792-17-1

1003709-39-4

2-Bromo-4-fluoro-5-methylbenzaldehyde (purchased from 3B Scientific Corporation, 1840 Industrial Drive, Suite 160, Libertyville, IL 60048, USA; 1.0 g, 4.61 mmol) was used as a raw material, which was mixed with sulfamic acid (2.68 g 27.65 mmol), sodium chlorite (539 mg, 6 mmol) and KH2PO4 (7.52 g, 55.3 mmol) in a 50% aqueous dioxane solution (96 mL). The reaction mixture was stirred overnight at room temperature. After the reaction was completed, the mixture was concentrated and diluted with water (20 mL). The resulting mixture was extracted with ethyl acetate (3 x 250 mL). The organic layers were combined, dried over anhydrous sodium sulfate, filtered and the solvent evaporated to give 2-bromo-4-fluoro-5-methylbenzoic acid (1.0 g, 93% yield) as an off-white solid. Mass spectrometry analysis: calculated value C8H6BrFO2 [M-H]? 231, measured value 231.0.

References

[1] Patent: WO2014/76104, 2014, A1. Location in patent: Page/Page column 76

2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-BROMO-4-FLUORO-5-METHYLBENZOIC ACID Suppliers

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