ChemicalBook > CAS DataBase List > 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)

2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)

Product Name
2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)
CAS No.
2192215-81-7
Chemical Name
2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)
Synonyms
PF-06651600 tosylate;Ritlecitinib tosylate;2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)
CBNumber
CB211015866
Molecular Formula
C22H27N5O4S
Formula Weight
457.55
MOL File
2192215-81-7.mol
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2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) Property

form 
Solid
color 
White to off-white
InChIKey
YOZLVAFWYLSRRN-NFGOAHBONA-N
SMILES
S(C1C=CC(C)=CC=1)(O)(=O)=O.N([C@@H]1CC[C@H](C)N(C(=O)C=C)C1)C1N=CN=C2NC=CC=12 |&1:12,15,r|
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Hazard and Precautionary Statements (GHS)

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2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) Chemical Properties,Usage,Production

Uses

Ritlecitinib tosylate is an orally active and selective JAK3 inhibitor with an IC50 of 33.1 nM. Ritlecitinib tosylate is used for inflammatory and autoimmune diseases research[1].

References

[1] Telliez JB, et al. Discovery of a JAK3-Selective Inhibitor: Functional Differentiation of JAK3-Selective Inhibition over pan-JAK or JAK1-Selective Inhibition. ACS Chem Biol. 2016 Dec 16;11(12):3442-3451. DOI:10.1021/acschembio.6b00677

2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) Suppliers

China 61 United States 1 Global 62
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
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View Lastest Price from 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1) manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Ritlecitinib Tosylate 2192215-81-7
Price
US $0.00/G
Min. Order
1G
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-07-24
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Ritlecitinib Tosylate. 2192215-81-7
Price
US $0.00/G
Min. Order
1G
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2025-01-07
Hangzhou Hyper Chemicals Limited
Product
Ritlecitinib Tosylate 2192215-81-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2024-04-09

2192215-81-7, 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)Related Search:


  • 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-, 4-methylbenzenesulfonate (1:1)
  • Ritlecitinib tosylate
  • PF-06651600 tosylate
  • 2192215-81-7
  • API