2,6-DIMETHYL-4-FLUOROBENZOIC ACID
- Product Name
- 2,6-DIMETHYL-4-FLUOROBENZOIC ACID
- CAS No.
- 16633-50-4
- Chemical Name
- 2,6-DIMETHYL-4-FLUOROBENZOIC ACID
- Synonyms
- 4-FLUORO-2,6-DIMETHYLBENZOIC ACID;RARECHEM AL BO 1056;2-Carboxy-5-fluoro-m-xylene;2,6-DIMETHYL-4-FLUOROBENZOIC ACID;2,6-Dimethyl-4-fluorobenzoicacid97%;Benzoic acid, 4-fluoro-2,6-dimethyl-;4-Fluoro-2,6-dimethyl benzoic acid - [F71840]
- CBNumber
- CB2111265
- Molecular Formula
- C9H9FO2
- Formula Weight
- 168.16
- MOL File
- Mol file
2,6-DIMETHYL-4-FLUOROBENZOIC ACID Property
- Boiling point:
- 278.4±35.0 °C(Predicted)
- Density
- 1.212
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder
- pka
- 3.53±0.37(Predicted)
- color
- Off-white
- Sensitive
- Air Sensitive
Safety
- Hazard Codes
- Xi
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D462063
- Product name
- 2,6-Dimethyl-4-fluorobenzoicAcid
- Packaging
- 500mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- 2721-3-Y5
- Product name
- 2,6-Dimethyl-4-fluorobenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $328
- Updated
- 2021/12/16
- Product number
- W3618
- Product name
- 2,6-Dimethyl-4-fluorobenzoicacid
- Packaging
- 100mg
- Price
- $134
- Updated
- 2021/12/16
- Product number
- PC8961
- Product name
- 2,6-Dimethyl-4-fluorobenzoicacid
- Packaging
- 1g
- Price
- $205
- Updated
- 2021/12/16
- Product number
- 082269
- Product name
- 4-Fluoro-2,6-dimethylbenzoic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $470
- Updated
- 2021/12/16
2,6-DIMETHYL-4-FLUOROBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
14659-60-0
16633-50-4
General procedure for the synthesis of 2,6-dimethyl-4-fluorobenzoic acid from methyl 2,6-dimethyl-4-fluorobenzoate: 4-amino-2,6-dimethylbenzoic acid (200 mg, 1.1 mmol) was heated and reacted with NOBF4 (196 mg, 1.7 mmol) in 1,2-dichlorobenzene at 100 °C for 30 min. Upon completion of the reaction, the reaction solution was cooled to room temperature and subsequently diluted with methanol and water. A few potassium hydroxide pellets (2-3 pellets) were added to the solution and the mixture was heated to reflux for 16 hours. At the end of the reaction, the solution was concentrated. The residue was partitioned between ether and 1N sodium hydroxide solution. The aqueous layer was extracted with ether. The aqueous layer was cooled to 0°C and acidified with concentrated hydrochloric acid to pH=1-2. The acidified aqueous layer was extracted with dichloromethane. The organic layers were combined and dried over anhydrous sodium sulfate. The dried organic layer was filtered and concentrated to give 58 mg (31% yield) of the target product 2,6-dimethyl-4-fluorobenzoic acid as a brown solid.
References
[1] Patent: EP1175401, 2005, B1. Location in patent: Page/Page column 30
[2] Patent: US6391865, 2002, B1. Location in patent: Page column 46
2,6-DIMETHYL-4-FLUOROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-DIMETHYL-4-FLUOROBENZOIC ACID manufacturers
- Product
- 2,6-Dimethyl-4-fluorobenzoic acid 16633-50-4
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-07
- Product
- 2,6-DIMETHYL-4-FLUOROBENZOIC ACID 16633-50-4
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-10