Pivopril

Product Name: Pivopril
CAS No.: 81045-50-3
Chemical Name: Pivopril
Synonyms: Pivopril;RHC 3659(S);N-Cyclopentyl-N-[(S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]glycine;Glycine, N-cyclopentyl-N-[(2S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]-
CBNumber: CB21116119
Molecular Formula: C16H27NO4S
Formula Weight: 329.45
MOL File: 81045-50-3.mol

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Pivopril Property

Boiling point:: 490.4±38.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 3.49±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0012294
Product name: PIVOPRIL
Purity: 95.00%
Packaging: 5MG
Price: $504.47
Updated: 2021/12/16

CSNpharm

Product number: CSN21805
Product name: Pivopril
Packaging: 1mg
Price: $592
Updated: 2021/12/16

CSNpharm

Product number: CSN21805
Product name: Pivopril
Packaging: 5mg
Price: $1173
Updated: 2021/12/16

CSNpharm

Product number: CSN21805
Product name: Pivopril
Packaging: 10mg
Price: $1999
Updated: 2021/12/16

CSNpharm

Product number: CSN21805
Product name: Pivopril
Packaging: 25mg
Price: $3519
Updated: 2021/12/16

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Pivopril Chemical Properties,Usage,Production

Uses

Antihypertensive.

Definition

ChEBI: Pivopril is a N-acyl-amino acid.

in vivo

Pivalopril is a new compound with a hindered sulfur group that has been compared to Captopril for oral angiotensin-converting enzyme (ACE) inhibition in rats and dogs and antihypertensive activity in rats. In separate groups of conscious normotensive rats, Pivalopril (0.03-1.0 mg/kg, orally [p.o.]) produces a dose-related antagonism of angiotensin I (AngI)-induced pressor effects. The ED₅₀ for Pivalopril and Captopril is 0.1 mg/kg. In conscious normotensive dogs, Pivalopril (incremental doses of 0.01-1.0 mg/kg, p.o.) produces a dose-related antagonism of AngI pressor effects. The ED₅₀ is 0.17 mg/kg for Pivalopril and 0.06 mg/kg for Captopril. At equieffective doses the two compounds have similar durations of action. In sodium-deficient, conscious spontaneously hypertensive rats (SHR), Pivalopril (1-100 mg/kg, p.o.) produces a dose-related reduction in mean arterial pressure. The potency and duration are similar to those of Captopril. In the sodium-replete SHR, 5 days of oral dosing with Pivalopril (100 mg/kg per day) decreases mean arterial pressure more effectively than Captopril (100 mg/kg per day). It is concluded that Pivalopril is a potent, orally effective ACE inhibitor and antihypertensive agent^[2].

Pivopril Preparation Products And Raw materials

Raw materials

Preparation Products

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Pivopril Suppliers

China 11 United Kingdom 1 United States 7 Global 19

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9751
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

cjbscvictory

Tel: 13348960310
Email: 3003867561@qq.com
Country: China
ProdList: 10503
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

RD International Technology Co., Limited

Tel: 18024082417
Email: market@ubiochem.com
Country: China
ProdList: 9835
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81136151 17392212881
Email: 1095@dideu.com
Country: China
ProdList: 10001
Advantage: 58

81045-50-3, PivoprilRelated Search:

N-(3-MERCAPTO-2-METHYLPROPANOYL)GLYCINE TERT-AMYL METHYL SULPHIDE trimethylthioacetic S-acid DIISOBUTYL SULFIDE Pivopril N-CYCLOPENTYL-N-METHYLGLYCINE N-PROPYL 3-MERCAPTOPROPIONATE 2-CYCLOPENTYLAMINO-ETHANOL

Pivopril

N-Cyclopentyl-N-[(S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]glycine

RHC 3659(S)

Glycine, N-cyclopentyl-N-[(2S)-3-[(2,2-dimethyl-1-oxopropyl)thio]-2-methyl-1-oxopropyl]-

81045-50-3

C16H27NO4S