Asocainol
- Product Name
- Asocainol
- CAS No.
- 77400-65-8
- Chemical Name
- Asocainol
- Synonyms
- Go-4704;Goe-4704;Asocainol;6,7,8,9-Tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-5H-dibenz[d,f]azonin-1-ol;5H-Dibenz[d,f]azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
- CBNumber
- CB21117181
- Molecular Formula
- C27H31NO3
- Formula Weight
- 417.54
- MOL File
- 77400-65-8.mol
N-Bromosuccinimide Price
- Product number
- A788500
- Product name
- Asocainol
- Packaging
- 25mg
- Price
- $1540
- Updated
- 2021/12/16
- Product number
- API0007937
- Product name
- ASOCAINOL
- Purity
- 95.00%
- Packaging
- 25MG
- Price
- $2194.5
- Updated
- 2021/12/16
- Product number
- API0007937
- Product name
- ASOCAINOL
- Purity
- 95.00%
- Packaging
- 2.5MG
- Price
- $742.5
- Updated
- 2021/12/16
Asocainol Chemical Properties,Usage,Production
Originator
Asocainol,ZYF Pharm
Uses
Asocainol (ASOC) belongs to class I antiarrhythmic drugs, i.e., those that exert their action at the level of sodium channels of the myocardial cell membrane.
Uses
Labelled Asocainol
Manufacturing Process
A solution of a Grignard reagent is prepared from 5.5 g (0.23 mol) activated magnesium turnings and 41.5 g (0.24 mol) phenethyl bromide in 200 ml anhydrous diethyl ether. To this is added dropwise, at 35-40°C, a solution of 31.5 g (0.1 mol) thebaine in 0.4 liters dry benzene. After heating under reflux for 2 hours, the reaction mixture is decomposed with a solution of 48 g ammonium chloride in 200 ml water. The usual working up, after conversion of the base into the hydrochloride by means of hydrogen chloride in ethyl acetate, gives 7.3 g (21% of theory) (+/-)-2,12-dimethoxy-1-hydroxy-7- methyl-6-phenethyl-5,6,8,9-tetrahydro-7H-dibenz[d,f]azonine hydrochloride, melting point 227.6°C, after recrystallization from propan-2-ol.
Therapeutic Function
Antiarrhythmic
Asocainol Preparation Products And Raw materials
Raw materials
Preparation Products
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