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Asocainol

Product Name
Asocainol
CAS No.
77400-65-8
Chemical Name
Asocainol
Synonyms
Go-4704;Goe-4704;Asocainol;6,7,8,9-Tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-5H-dibenz[d,f]azonin-1-ol;5H-Dibenz[d,f]azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
CBNumber
CB21117181
Molecular Formula
C27H31NO3
Formula Weight
417.54
MOL File
77400-65-8.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
A788500
Product name
Asocainol
Packaging
25mg
Price
$1540
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007937
Product name
ASOCAINOL
Purity
95.00%
Packaging
25MG
Price
$2194.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0007937
Product name
ASOCAINOL
Purity
95.00%
Packaging
2.5MG
Price
$742.5
Updated
2021/12/16
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Asocainol Chemical Properties,Usage,Production

Originator

Asocainol,ZYF Pharm

Uses

Asocainol (ASOC) belongs to class I antiarrhythmic drugs, i.e., those that exert their action at the level of sodium channels of the myocardial cell membrane.

Uses

Labelled Asocainol

Manufacturing Process

A solution of a Grignard reagent is prepared from 5.5 g (0.23 mol) activated magnesium turnings and 41.5 g (0.24 mol) phenethyl bromide in 200 ml anhydrous diethyl ether. To this is added dropwise, at 35-40°C, a solution of 31.5 g (0.1 mol) thebaine in 0.4 liters dry benzene. After heating under reflux for 2 hours, the reaction mixture is decomposed with a solution of 48 g ammonium chloride in 200 ml water. The usual working up, after conversion of the base into the hydrochloride by means of hydrogen chloride in ethyl acetate, gives 7.3 g (21% of theory) (+/-)-2,12-dimethoxy-1-hydroxy-7- methyl-6-phenethyl-5,6,8,9-tetrahydro-7H-dibenz[d,f]azonine hydrochloride, melting point 227.6°C, after recrystallization from propan-2-ol.

Therapeutic Function

Antiarrhythmic

Asocainol Preparation Products And Raw materials

Raw materials

Preparation Products

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Asocainol Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55954
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28180
Advantage
58

77400-65-8, AsocainolRelated Search:


  • Asocainol
  • 6,7,8,9-Tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-5H-dibenz[d,f]azonin-1-ol
  • Go-4704
  • Goe-4704
  • 5H-Dibenz[d,f]azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-
  • 77400-65-8
  • C27H31NO3
  • C27H26D5NO3
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Isotope Labelled Compounds
  • Pharmaceuticals