ChemicalBook > CAS DataBase List > Satigrel
Satigrel
- Product Name
- Satigrel
- CAS No.
- 111753-73-2
- Chemical Name
- Satigrel
- Synonyms
- E-5510;Satigrel;4-Cyano-5,5-bis(4-methoxyphenyl)-4-pentenoic acid;4-cyano-5,5-bis(4-methoxyphenyl)pent-4-enoic acid;4-Pentenoic acid, 4-cyano-5,5-bis(4-methoxyphenyl)-
- CBNumber
- CB21117808
- Molecular Formula
- C20H19NO4
- Formula Weight
- 337.373
- MOL File
- 111753-73-2.mol
More
Less
Satigrel Property
- Melting point:
- 124-125°
- form
- Solid
- color
- White to off-white
More
Less
Safety
- Toxicity
- LD50 oral in rat: 337mg/kg
More
Less
N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0012467
- Product name
- SATIGREL
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $495.81
- Updated
- 2021/12/16
More
Less
Satigrel Chemical Properties,Usage,Production
Uses
Satigrel (E5510) is a potent inhibitor of platelet aggregation. Satigrel inhibits collagen- and arachidonic acid-induced platelet aggregation through preventing thromboxane A2 synthesis by selective inhibition of the target enzyme, PGHS1, which exists in platelets. Satigrel inhibits PGHS1 (IC50: 0.081 μM) and PGHS2 (IC50: 5.9 μM). Satigrel is against Type III PDE, Type V and Type II (IC50: 15.7 μM, 39.8 μM and 62.4 μM, respectively)[1].
References
[1] N Nagakura, et al. Mechanisms of satigrel (E5510), a new anti-platelet drug, in inhibiting human platelet aggregation. Selectivity and potency against prostaglandin H synthases isozyme activities and phosphodiesterase isoform activities. Biol Pharm Bull. 1996 Jun;19(6):828-33. DOI:10.1248/bpb.19.828
Satigrel Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Satigrel Suppliers
- Tel
- 18939837085
- Fax
- 2880152141(QQ)
- youchemicals@gmail.com
- Country
- China
- ProdList
- 1839
- Advantage
- 55
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29257
- Advantage
- 58
- Tel
- +86-571-87711850
- market18@leapchem.com
- Country
- China
- ProdList
- 43339
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@lanospharma.com
- Country
- China
- ProdList
- 6329
- Advantage
- 56