Darodipine
- Product Name
- Darodipine
- CAS No.
- 72803-02-2
- Chemical Name
- Darodipine
- Synonyms
- PY-108068;PY-108063;PY-108-068;Darodipine;Darodipine(PY-108068);Darodipine, 10 mM in DMSO;diethyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate;PY108068,Ca channels,PY 108068,Calcium Channel,Darodipine,Ca2+ channels,Inhibitor,inhibit;4-(Benzofurazan-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester;3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3,5-diethyl ester
- CBNumber
- CB21118007
- Molecular Formula
- C19H21N3O5
- Formula Weight
- 371.39
- MOL File
- 72803-02-2.mol
Darodipine Property
- Melting point:
- 148-151°C
- storage temp.
- Refrigerator
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- Pale Yellow to Light Yellow
- InChI
- InChI=1S/C19H21N3O5/c1-5-25-18(23)14-10(3)20-11(4)15(19(24)26-6-2)16(14)12-8-7-9-13-17(12)22-27-21-13/h7-9,16,20H,5-6H2,1-4H3
- InChIKey
- QERUYFVNIOLCHV-UHFFFAOYSA-N
- SMILES
- C1(C)NC(C)=C(C(OCC)=O)C(C2C3C(C=CC=2)=NON=3)C=1C(OCC)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- API0005905
- Product name
- DARODIPINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.16
- Updated
- 2021/12/16
- Product number
- 56295
- Product name
- Darodipine
- Packaging
- 25mg
- Price
- $650
- Updated
- 2021/12/16
Darodipine Chemical Properties,Usage,Production
Uses
Antihypertensive; bronchodilator; vasodilator.
Uses
Darodipine is a calcium channel antagonist.
in vivo
Treatment with darodipine increases the number and the average length of alkaline phosphatase-reactive capillaries and reduces the intercapillary distance and the diameter of cerebral capillaries in old rats. The pericapillary microrenvironment of the Ammon’s horn is the most sensitive to treatment with darodipine[1]. Darodipine may reduce neuronal cytoskeletal changes occurring in aging and in neurodegenerative disorders. A 6-month treatment (from the 18th to the 24th month of life) with an oral daily dose of 10 mg/kg of darodipine restores in part the expression of 200 kDa-NF subunit immunoreactivity in the cerebellar cortex[2].
Darodipine Preparation Products And Raw materials
Raw materials
Preparation Products
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