Malabaricone C
- Product Name
- Malabaricone C
- CAS No.
- 63335-25-1
- Chemical Name
- Malabaricone C
- Synonyms
- Malabaricone C;1-(2,6-Dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-1-nonanone;1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)nonan-1-one;1-Nonanone, 1-(2,6-dihydroxyphenyl)-9-(3,4-dihydroxyphenyl)-;lipid metabolism,Inhibitor,sphingomyelin synthase,SMS 1,diet,obesity,inhibit,Malabaricone C,SMS 2
- CBNumber
- CB21120408
- Molecular Formula
- C21H26O5
- Formula Weight
- 358.43
- MOL File
- 63335-25-1.mol
Malabaricone C Property
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml
- form
- A crystalline solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- 29741
- Product name
- Malabaricone C
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 29741
- Product name
- Malabaricone C
- Packaging
- 25mg
- Price
- $748
- Updated
- 2024/03/01
- Product number
- 29741
- Product name
- Malabaricone C
- Packaging
- 5mg
- Price
- $169
- Updated
- 2024/03/01
- Product number
- 29741
- Product name
- Malabaricone C
- Packaging
- 10mg
- Price
- $319
- Updated
- 2024/03/01
- Product number
- 7286CA
- Product name
- MalabariconeC
- Packaging
- 1mg
- Price
- $139
- Updated
- 2021/12/16
Malabaricone C Chemical Properties,Usage,Production
Description
Malabaricone C is a diarylnonanoid that has been found in Myristica and has diverse biological activities. It scavenges 59.9% of 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals when used at a concentration of 7 μg/ml. Malabaricone C is active against S. aureus, B. subtilis, and C. albicans in vitro (MICs = 2-32 μg/ml). It is cytotoxic to A549, HL-60, and MCF-7 cells (IC50s = 12.3, 46.1, and 10.8 μM, respectively). Malabaricone C inhibits sphingomyelin synthase 1 (SMS1) and SMS2 activity in cell lysates (IC50s = 3 and 1.5 μM, respectively). It decreases body weight gain, hepatic steatosis, and hepatic and plasma triglyceride levels in a mouse model of high-fat diet-induced obesity when administered at a dose of 0.1% in the diet.
Uses
Malabaricone C is a useful research chemical compound from Myristica malabarica which exhibits antioxidant activity.
Definition
ChEBI: A natural product found in Myristica cinnamomea.
Malabaricone C Preparation Products And Raw materials
Raw materials
Preparation Products
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