ChemicalBook > CAS DataBase List > 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
- Product Name
- 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
- CAS No.
- 218137-86-1
- Chemical Name
- 3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE
- Synonyms
- C75;FAS inhibitor C75 (C-75;C75 >=98% (HPLC), powder;3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE;TRANS-4-CARBOXY-5-OCTYL-3-METHYLENEBUTYROLACTONE;3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-;C75(4-Methylene-2-octyl-5-oxo-tetrahydro-furan-3-carboxylicacid);TRANS-TETRAHYDRO-3-METHYLENE-2-OXO-5-N-OCTYL-4-FURANCARBOXYLIC ACID
- CBNumber
- CB2114165
- Molecular Formula
- C14H22O4
- Formula Weight
- 254.32
- MOL File
- 218137-86-1.mol
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Property
- Boiling point:
- 432.1±45.0 °C(Predicted)
- Density
- 1.08±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 18 mg/mL
- form
- solid
- pka
- 3.08±0.40(Predicted)
- color
- off-white
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Safety
- WGK Germany
- 3
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- C5490
- Product name
- C75
- Purity
- ≥98% (HPLC), powder
- Packaging
- 5mg
- Price
- $345
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- C5490
- Product name
- C75
- Purity
- ≥98% (HPLC), powder
- Packaging
- 25mg
- Price
- $1390
- Updated
- 2024/03/01
Tocris
- Product number
- 2489
- Product name
- C75
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $227
- Updated
- 2021/12/16
Usbiological
- Product number
- 254848
- Product name
- C 75
- Packaging
- 10mg
- Price
- $480
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-3562
- Product name
- C75
- Purity
- 99.91%
- Packaging
- 50mg
- Price
- $842
- Updated
- 2021/12/16
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Chemical Properties,Usage,Production
Uses
C75 has been used:
- as a fatty acid synthase (FASN) inhibitor to test its ability in the direct inhibition of FASN to attenuate mammosphere formation as compared to metformin
- as a pharmacological inhibitor to inhibit fatty acid synthesis in glioma stem cells (GSCs)
- as FAS inhibitor in the pre-treatment of Chang cells to inhibit lipogenesis and reverse the senescence induced by hydrogen peroxide
Definition
ChEBI: 4-methylene-2-octyl-5-oxo-3-oxolanecarboxylic acid is a gamma-lactone.
Biochem/physiol Actions
C75 helps to increase the cancer‐killing capability of ionizing radiation.
3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Preparation Products And Raw materials
Raw materials
Preparation Products
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3-CARBOXY-4-OCTYL-2-METHYLENEBUTYROLACTONE Suppliers
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