Saredutant

Product Name: Saredutant
CAS No.: 142001-63-6
Chemical Name: Saredutant
Synonyms: SR 48968;Sr 48968c;(S)-N-Methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide;Benzamide, N-((2S)-4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-;Benzamide, N-(4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-, (S)-
CBNumber: CB21179709
Molecular Formula: C31H35Cl2N3O2
Formula Weight: 552.53
MOL File: 142001-63-6.mol

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Saredutant Property

Boiling point:: 734.7±60.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 250 mg/mL (452.46 mM)
pka: 15.88±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P314Get medical advice/attention if you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0026895
Product name: Saredutant
Purity: 99.30%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0026895
Product name: Saredutant
Purity: 99.30%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0026895
Product name: Saredutant
Purity: 99.30%
Packaging: 25mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0026895
Product name: Saredutant
Purity: 99.30%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0026895
Product name: Saredutant
Purity: 99.30%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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Saredutant Chemical Properties,Usage,Production

Uses

Saredutant is a selective NK2 receptor antagonist.

in vivo

Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility^[1].

IC 50

NK2

References

[1] Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96(2):206-10. DOI:10.1016/j.pbb.2010.05.006

Saredutant Preparation Products And Raw materials

Raw materials

Preparation Products

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Saredutant Suppliers

China 15 India 1 United States 6 Global 22

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

BOC Sciences

Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 12952
Advantage: 65

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

142001-63-6, SaredutantRelated Search:

Saredutant N8-ACETYLSPERMIDINE DIHYDROCHLORIDE 3-PHENYL-3-PENTYLAMINE HYDROCHLORIDE SR 48968, [BENZAMIDE-4-3H]- N-[2-(4-CHLORO-PHENYL)-ETHYL]-BENZAMIDE N-Methyl-4-phenyl-4-piperidinamine [3H]SR 48968

SR 48968

(S)-N-Methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide

Benzamide, N-((2S)-4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-

Benzamide, N-(4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-, (S)-

Sr 48968c

142001-63-6