ChemicalBook > CAS DataBase List > 5,10-Methylene-THF

5,10-Methylene-THF

Product Name
5,10-Methylene-THF
CAS No.
31690-11-6
Chemical Name
5,10-Methylene-THF
Synonyms
5,10-Methylene-THF;Folinic Acid Impurity 7;Folic Acid EP Impurity I;Levofolinate EP Impurity I;Folinic Acid EP Impurity I;(S)-2-(4-((R)-3-amino-1-oxo;Calcium Levofolinate EP Impurity I;(6R) 5,10-Methylenetetrahydrofolate;(6aR)-5,10-Methylenetetrahydrofolic Acid;N5,N10-Methylene-5,6,7,8-tetrahydrofolate
CBNumber
CB21235571
Molecular Formula
C20H23N7O6
Formula Weight
457.44
MOL File
31690-11-6.mol
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5,10-Methylene-THF Property

Density 
1.75±0.1 g/cm3(Predicted)
pka
3.47±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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5,10-Methylene-THF Chemical Properties,Usage,Production

Uses

Arfolitixorin is a folate prodrug that is used in the treatment for colorectal cancer as a way for increase in efficacy and reducing the side effects of antimetabolites used in cancer treatment.

Definition

ChEBI: (6R)-5,10-methylenetetrahydrofolic acid is the (6R)-stereoisomer of 5,10-methylenetetrahydrofolic acid. It has a role as an Escherichia coli metabolite, a mouse metabolite and a cofactor. It is a conjugate acid of a (6R)-5,10-methylenetetrahydrofolate(2-).

5,10-Methylene-THF Preparation Products And Raw materials

Raw materials

Preparation Products

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5,10-Methylene-THF Suppliers

China 26 India 3 United States 3 Global 32
SynZeal Research Pvt Ltd
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--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
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Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58

31690-11-6, 5,10-Methylene-THFRelated Search:

(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6- yl]methylamino]benzoyl]amino]pentanedioic acid 10-Formylfolic Acid 5,10-DiforMyl-5,6,7,8-tetrahydro Folic Acid Folinic Acid IMpurity E Calcium levofolinate 10-formyldihydrofolate

  • 5,10-Methylene-THF
  • (6R) 5,10-Methylenetetrahydrofolate
  • 5,10-Methylene-THF// (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydro imidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzami do)pentanedioic acid
  • N5,N10-Methylene-5,6,7,8-tetrahydrofolate
  • (S)-2-(4-((R)-3-amino-1-oxo
  • (S)-2-(4-((R)-3-Amino-1-oxo-5,6,6a,7-tetrahydroimidazo[1,5-f]pteridin-8(1H,4H,9H)-yl)benzamido)pentanedioic acid
  • L-Glutamic acid, N-[4-[(6aR)-3-amino-1,2,5,6,6a,7-hexahydro-1-oxoimidazo[1,5-f]pteridin-8(9H)-yl]benzoyl]-
  • Folinic Acid EP Impurity I
  • Folinic Acid Impurity 7
  • Calcium Levofolinate EP Impurity I
  • Levofolinate EP Impurity I
  • (6aR)-5,10-Methylenetetrahydrofolic Acid
  • Folic Acid EP Impurity I
  • Calcium Levofolinate Impurity 10 (Calcium Levofolinate EP Impurity I)
  • Levofolinate EP Impurity I（Folic Acid EP Impurity I）
  • 31690-11-6
  • C20H23N7O6