2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid
- Product Name
- 2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid
- CAS No.
- 120-02-5
- Chemical Name
- 2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid
- Synonyms
- Thiocarbarsone;[p-Ureidophenylarsylenebis(thio)]diacetic acid;2-[[(carboxymethylthio)-(4-ureidophenyl)arsino]thio]acetic acid;Acetic acid, 2,2'-[[[4-[(aminocarbonyl)amino]phenyl]arsinidene]bis(thio)]bis-;2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid;2-[[4-(aminocarbonylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanylethanoic acid
- CBNumber
- CB21261082
- Molecular Formula
- C11H13AsN2O5S2
- Formula Weight
- 392.28
- MOL File
- 120-02-5.mol
2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid Property
- CAS DataBase Reference
- 120-02-5
N-Bromosuccinimide Price
- Product number
- API0025725
- Product name
- THIOCARBARSONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.04
- Updated
- 2021/12/16
2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid Chemical Properties,Usage,Production
Originator
Thiocarbarsone,Lilly,US,1951
Manufacturing Process
121 g of thioglycolic acid and 100 g of carbarsone oxide are reacted in a
solution of 128 g of sodium bicarbonate in 2 liters of water.
The mixture is heated on a steam bath for 20 minutes. The reaction mixture is then cooled and filtered to remove a small amount of insoluble material.
The filtrate is diluted with about 600 cc of water and is acidified with
concentrated hydrochloric acid.
On treating the reaction mixture with acid, di-(carboxymethylthio)-pcarbamidophenylarsine
precipitates, and is separated by filtration and dried.
Di -(carboxymethylthio)-p-carbamidophenylarsine thus prepared was obtained
as a white amorphous solid, soluble in dilute alkali. It contained about 19.85%
of arsenic as compared with the calculated amount of 19.09%.
Therapeutic Function
Antiamebic
Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. See also ARSENIC COMPOUNDS, MERCAPTANS, and ESTERS. When heated to decomposition it emits very toxic fumes of As and SOx
2-[[4-(carbamoylamino)phenyl]-(carboxymethylsulfanyl)arsanyl]sulfanyla cetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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