ChemicalBook > CAS DataBase List > ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT
ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT
- Product Name
- ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT
- Chemical Name
- ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT
- Synonyms
- HEK-1 trifluoroacetate salt;Hemokinin 1 mouse, rat trifluoroacetate salt;ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT
- CBNumber
- CB2129532
- Molecular Formula
- C63H101F3N22O17S
- Formula Weight
- 1527.67
- MOL File
- Mol file
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ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT Property
- storage temp.
- −20°C
- solubility
- H2O: soluble
- form
- powder
- color
- white
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT Chemical Properties,Usage,Production
Description
Hemokinin 1 is an 11-amino acid tachykinin neuropeptide with roles in pain transmission and inflammation and is a neurokinin-1 (NK1) receptor agonist.1,2 It is primarily expressed in immune cells and, to a lesser extent, in the brain.3 Hemokinin 1 binds to NK1 receptors (Ki = 0.175 nM) and induces contractions in isolated rat urinary bladder (EC50 = 100 nM).1 Knockdown of Tac4, the gene encoding hemokinin 1, inhibits neurogenic inflammation-induced mechanical and thermal hypersensitivity and visceral nocifensive behavior in mice.3 Tac4-/- mice also exhibit impaired inflammatory responses to intranasal administration of E. coli LPS.4WARNING This product is not for human or veterinary use.
ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT Preparation Products And Raw materials
Raw materials
Preparation Products
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ARG-SER-ARG-THR-ARG-GLN-PHE-TYR-GLY-LEU-MET-NH2 TFA SALT Suppliers
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