ChemicalBook > CAS DataBase List > TAS 103
TAS 103
- Product Name
- TAS 103
- CAS No.
- 174634-08-3
- Chemical Name
- TAS 103
- Synonyms
- TAS 103;CS-1287;BMS-247615;TAS-103 HC1;TAS-103 base;TAS-103(salt);TA103(bms-247615);6-[[2-(Dimethylamino)ethyl]amino]-3-hydroxy-7H-indeno[2,1-c]quinolin-7-one;7H-Indeno[2,1-c]quinolin-7-one, 6-[[2-(dimethylamino)ethyl]amino]-3-hydroxy-
- CBNumber
- CB21321579
- Molecular Formula
- C20H19N3O2
- Formula Weight
- 333.38
- MOL File
- 174634-08-3.mol
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TAS 103 Property
- Melting point:
- 216-217 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 589.5±50.0 °C(Predicted)
- Density
- 1.350±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 7.88±0.20(Predicted)
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N-Bromosuccinimide Price
Crysdot
- Product number
- CD31002974
- Product name
- TAS-103
- Purity
- 98+%
- Packaging
- 5mg
- Price
- $83
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31002974
- Product name
- TAS-103
- Purity
- 98+%
- Packaging
- 10mg
- Price
- $132
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31002974
- Product name
- TAS-103
- Purity
- 98+%
- Packaging
- 50mg
- Price
- $381
- Updated
- 2021/12/16
Crysdot
- Product number
- CD31002974
- Product name
- TAS-103
- Purity
- 98+%
- Packaging
- 100mg
- Price
- $658
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC7898
- Product name
- TAS-103(BMS247615)
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1100
- Updated
- 2021/12/16
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TAS 103 Chemical Properties,Usage,Production
Biological Activity
TAS-103 is a dual DNA topoisomerase I/II (topoisomerase I/II) inhibitor for cancer research.
in vivo
TAS-103 (30 mg/kg, iv) causes significant tumor growth suppression in mice bearing Lewis lung carcinoma (LLC) cells, without obvious body weight loss, and the liposomal TAS-103 is more active than free TAS-103.
target
| Topoisomerase I
| Topoisomerase II
|
TAS 103 Preparation Products And Raw materials
Raw materials
Preparation Products
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