ChemicalBook > CAS DataBase List > Polyglutamic acid

Polyglutamic acid

Product Name
Polyglutamic acid
CAS No.
25513-46-6
Chemical Name
Polyglutamic acid
Synonyms
γ-PGA;Y-Polyglutamic Acid;y-PGA;γ-Polyglutamic acid;alpha-l-glutamicacidpolymer;Poly-γ-Glutamic Acid(γ-PGA);POLY-L;Polyglutamicaci;poly-l-glutamate;γ- polyglutamate
CBNumber
CB2132778
Molecular Formula
C5H9NO4
Formula Weight
147.13
MOL File
25513-46-6.mol
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Polyglutamic acid Property

storage temp. 
−20°C
InChI
InChI=1/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/s3
InChIKey
WHUUTDBJXJRKMK-ZJPLZJKBNA-N
SMILES
[C@@H](N)(C(=O)O)CCC(=O)O |&1:0,r|
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Safety

WGK Germany 
3
RTECS 
MA1700000
3-10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0043360
Product name
γ-Polyglutamicacidγ-PGA
Packaging
10g
Price
$115
Updated
2021/12/16
ChemScene
Product number
CS-0043360
Product name
γ-Polyglutamicacidγ-PGA
Packaging
25g
Price
$230
Updated
2021/12/16
Labseeker
Product number
SC-19546
Product name
POLY-L-GLUTAMICACID
Purity
分子量150万
Packaging
100g
Price
$400
Updated
2021/12/16
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Polyglutamic acid Chemical Properties,Usage,Production

Description

Polyglutamic acid (PGA), a poly amino acid produced by Bacillus spp. is a naturally occurring anionic, water-soluble, biodegradable, non-toxic, viscous, edible biopolymer containing D and L-glutamic acid residues with different industrial applications.

Uses

Polyglutamic acid is commonly used in cosmetics as a powerful humectant for moisturising the skin. It is ideal for people with dry or dehydrated skin and may help to reduce the appearance of fine lines and wrinkles. Polyglutamic acid is also used in the food industry and has the ability to improve taste and flavour. In addition, Polyglutamic acid is an environmentally friendly biomaterial that can be used as a drug carrier/delivery agent and as a contrast agent.

Definition

ChEBI: A macromolecule composed of repeating gamma-linked L-glutamyl units.

Application

Polyglutamic acid is considered a promising bio-based chemical and is already widely used in the food, medical, and wastewater industries due to its biodegradable, non-toxic, and non-immunogenic properties.

Preparation

The Preparation method of Polyglutamic acid is as follows:poplar sawdust was used to produce Polyglutamic acid. Poplar sawdust was treated with acid and then hydrolyzed with cellulose. The enzymatic hydrolysate was used to produce Polyglutamic acid. Through single factor and orthogonal experiments, the optimum enzymatic conditions were determined as follows: solid-liquid ratio 1:5, enzyme amount 22 FPU/g, pH 5.0 and 53 min. Under the enzymatic hydrolysate medium, the Polyglutamic acid yield reached 30.87 ± 0.44 g/L, which was 5.11% higher than that in glucose medium (29.37 ± 0.43 g/L). In addition, the amount of glucose added to the medium was reduced, which realized the comprehensive utilization of various sugars in sawdust enzymatic hydrolysate.

benefits

The primary benefit of polyglutamic acid is its impressive ability to hydrate skin. Because it’s a polymer, it forms a flexible, smooth, moisture-binding film on skin’s surface. This film helps skin keep moisture in its surface layers, even in conditions of low humidity, making polyglutamic acid an effective humectant. In addition to its abilities to aid skin in moisture retention, polyglutamic acid soothes and helps increase the production of natural moisturizing factors (NMF) in skin, which contributes to having a healthier barrier and balanced hydration. Polyglutamic acid hydrates skin but also performs other roles as well including wrinkle reduction, balancing the effects of chronic sun exposure and enhancing wound healing.

Side effects

Polyglutamic acid is generally considered safe and allergic reaction side effects are rare, which may result in itching, swelling, redness, burning sensation or blisters. Before applying Polyglutamic acid to your face, you can perform a patch test to ensure that you are tolerating this ingredient well.

Toxicology

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher

Polyglutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Polyglutamic acid Suppliers

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View Lastest Price from Polyglutamic acid manufacturers

Jinan Finer Chemical Co., Ltd
Product
γ-Polyglutamic acid 25513-46-6
Price
US $5.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500mt/year
Release date
2023-03-24
Hebei Longbang Technology Co., Ltd
Product
Polyglutamic acid 25513-46-6
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-05-08
Sinoway Industrial co., ltd.
Product
Poly-γ-Glutamic Acid(γ-PGA) 25513-46-6
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
100kDa, 90% up purity
Supply Ability
20 tons
Release date
2024-04-09

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