N-nitrosodibenzylamine
- Product Name
- N-nitrosodibenzylamine
- CAS No.
- 5336-53-8
- Chemical Name
- N-nitrosodibenzylamine
- Synonyms
- Dibenzylnitrosamine;Nitrosodibenzylamine;N,N-DIBENZYLNITROSAMINE;N,N-dibenzylnitrous amide;N-Nitrosodibenzylamine (NDBzA);N-Nitroso-N-benzylbenzenemethanamine;N-benzyl-N-nitroso-1-phenylmethanamine;Benzenemethanamine, N-nitroso-N-(phenylmethyl)-;N-nitrosodibenzylamine Solution in Methanol, 100μg/mL
- CBNumber
- CB21329999
- Molecular Formula
- C14H14N2O
- Formula Weight
- 226.27
- MOL File
- 5336-53-8.mol
N-nitrosodibenzylamine Property
- Melting point:
- 56-58°C
- Boiling point:
- 367.89°C (rough estimate)
- Density
- 1.0852 (rough estimate)
- refractive index
- 1.6419 (estimate)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Low-Melting Solid to Solid
- pka
- -5.91±0.70(Predicted)
- color
- Pale Yellow to Yellow
Safety
- Safety Statements
- 24/25
- HS Code
- 29214990
- Toxicity
- LD50 orl-rat: 900 mg/kg ZEKBAI 69,103,1967
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H350May cause cancer
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- N525450
- Product name
- N-Nitrosodibenzylamine
- Packaging
- 25mg
- Price
- $165
- Updated
- 2021/12/16
- Product number
- JK904589
- Product name
- N-Nitrosodibenzylamine
- Purity
- 98%
- Packaging
- 50mg
- Price
- $186
- Updated
- 2021/12/16
- Product number
- CHM0158205
- Product name
- N-NITROSODIBENZYLAMINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.63
- Updated
- 2021/12/16
N-nitrosodibenzylamine Chemical Properties,Usage,Production
Chemical Properties
Yellow Low Melting Solid
Uses
N-Nitrosodibenzylamine (NDBzA) is mutagenic to Salmonella typhimurium and induces DNA strand breaks in isolated rat hepatocytes.
Production Methods
Human exposure to NDBzA was not suspected, but then there were reports of the compound in hams wrapped in rubber netting. Concentrations of NDBzA from 10 to 100 ppb were common, and some were as high as 512 ppb. Like other nitrosamines in rubber, NDBzA arose by nitrosation of dialkylamino compounds (in this case dibenzyl-) during manufacture.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 2619, 1984 DOI: 10.1016/S0040-4039(01)81245-4
Safety Profile
Moderately toxic by ingestion.Mutation data reported. When heated to decomposition itemits toxic vapors of NOx
Carcinogenicity
There is a single report of a test of nitrosodibenzylamine for
carcinogenicity in rats using high doses and that is
completely negative; in contrast, nitrosobenzylphenylamine
is a weak, but definite, esophageal carcinogen in
rats. NDBzA is not mutagenic to bacteria in the
presence or absence of rat liver microsomes.
Although there is no information about metabolism and
activation of NDBzA, the alpha-acetoxy derivative (which
presumably is the ester of the alpha-hydroxy derivative that
would be formed in vivo) is both carcinogenic to rats and
mutagenic to bacteria.
N-nitrosodibenzylamine Preparation Products And Raw materials
Raw materials
Preparation Products
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