SDZ NVI-085

Product Name: SDZ NVI-085
CAS No.: 104195-17-7
Chemical Name: SDZ NVI-085
Synonyms: SDZ NVI-085;naphtoxazine;[4aR,(-)]-3,4,4aβ,5,10,10aα-Hexahydro-6-methoxy-4-methyl-9-methylthio-2H-naphth[2,3-b]-1,4-oxazine;2H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-
CBNumber: CB21335257
Molecular Formula: C15H21NO2S
Formula Weight: 279.4
MOL File: 104195-17-7.mol

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SDZ NVI-085 Property

Boiling point:: 417.6±45.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
pka: 7.45±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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SDZ NVI-085 Chemical Properties,Usage,Production

Description

SDZ-NVI-085, also known as Naphtoxazine, is an α1 adrenergic receptor agonist potentially for the treatment of cognitive disorders and major depressive disorder. SDZ-NVI-085 behaves as a competitive antagonist of 5-hydroxytryptamine. SDZ-NVI-085 shifted 5-HT concentration-effect curves to the right, in a concentration-dependent manner, and Schild regression gave a pA2 estimate of 8.0.

Uses

SDZ NVI 085 is a compound with CNS stimulatory effects, primarily through the α1-adrenoceptor subtype, with anti-cataplexy and anti-stroke activities. SDZ NVI 085 also has a significant alertness effect and can be used to study other types of excessive sleepiness[1].

References

[1] A Renaud, et al. Effects of SDZ NVI-085, a putative subtype-selective α1-agonist, on canine cataplexy, a disorder of rapid eye movement sleep. European journal of pharmacology 205.1 (1991): 11-16. DOI:10.1016/0014-2999(91)90763-g

SDZ NVI-085 Preparation Products And Raw materials

Raw materials

Preparation Products

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SDZ NVI-085 Suppliers

China 2 South Korea 1 United States 2 Global 5

TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

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Country: China
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TargetMol Chemicals Inc.

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Hangzhou MolCore BioPharmatech Co.,Ltd.

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104195-17-7, SDZ NVI-085Related Search:

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SDZ NVI-085

[4aR,(-)]-3,4,4aβ,5,10,10aα-Hexahydro-6-methoxy-4-methyl-9-methylthio-2H-naphth[2,3-b]-1,4-oxazine

naphtoxazine

2H-Naphth[2,3-b]-1,4-oxazine, 3,4,4a,5,10,10a-hexahydro-6-methoxy-4-methyl-9-(methylthio)-, (4aR,10aR)-

104195-17-7