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bruceine E

Product Name: bruceine E
CAS No.: 21586-90-3
Chemical Name: bruceine E
Synonyms: Brucein E;20-Deoxybruceine F;2-O-Demethylbruceine M;Bruceine E, 10 mM in DMSO;13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one;hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit;Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one;(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one
CBNumber: CB21340189
Molecular Formula: C20H28O9
Formula Weight: 412.43
MOL File: 21586-90-3.mol

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bruceine E Property

form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN89340
Product name: BruceineE
Purity: ≥98%
Packaging: 20mg
Price: $318
Updated: 2021/12/16

Arctom

Product number: SY232747
Product name: BruceineE
Purity: ≥98%
Packaging: 10mg
Price: $477.27
Updated: 2021/12/16

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bruceine E Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from the fruit of Brucea javanica.

Uses

Bruceine E is a quassinoid from seeds of Brucea javanica (L.) Merr, exhibiting hypoglycemia effect[1]. Bruceine E exhibits blood glucose lowering effect in both nondiabetic mice and Streptozotocin (STZ (HY-13753))-induced diabetic rats at lower dose[2].

in vivo

Bruceine D and E, isolated from B. javanica seeds, exhibits blood glucose lowering effect in both nondiabetic mice and STZ-induced diabetic rats at lower dose (1 mg/kg b.w.) during 0-8 h screening^[2].

References

[1] Man F, et al. HPLC-MS/MS method for bioavailability study of bruceines D & E in rat plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 15;1063:183-188. DOI:10.1016/j.jchromb.2017.08.037
[2] Ablat A, et al. Antidiabetic effects of Brucea javanica seeds in type 2 diabetic rats. BMC Complement Altern Med. 2017;17(1):94. Published 2017 Feb 6. DOI:10.1186/s12906-017-1610-x

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Raw materials

Preparation Products

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View Lastest Price from bruceine E manufacturers

Career Henan Chemical Co

Product: bruceine E 21586-90-3
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

21586-90-3, bruceine ERelated Search:

5-Decanolide Undecanolactone UNDECANOLIDE (-)-DIHYDROCARVYL ACETATE DIHYDROCARVEOL DELTA-TRIDECANOLACTONE delta-Dodecalactone 3,5,5-TRIMETHYL-2-CYCLOHEXEN-1-OL Pinacol (R)-BETA-HYDROXY-BETA-METHYL-DELTA-VALEROLACTONE (TETRAHYDRO-FURAN-3-YL)-ACETIC ACID DL-LEUCIC ACID 5-Hydroxyoctanoic acid lactone delta-Nonalactone Lactic acid isoamyl ester (R)-5-HEXANOLIDE ISO-PROPYL-UNDECYLENATE (R)-2-HYDROXY-4-METHYLPENTANOIC ACID

13,20-Epoxy-1β,2α,11β,12α,14,15β-hexahydroxypicras-3-en-16-one

20-Deoxybruceine F

2-O-Demethylbruceine M

Brucein E

Picras-3-en-16-one, 13,20-epoxy-1,2,11,12,14,15-hexahydroxy-, (1β,2α,11β,12α,15β)-

(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS)-1,2,3a,4,10,11-hexahydroxy-3,8,11a-trimethyl-2,3,3a,4,7,7a,10,11,11a,11b-decahydro-1H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5(6aH)-one

hypoglycemia,quassinoid,Bruceine E,effect,Inhibitor,antidiabetic,inhibit

(1R,2S,3R,3aR,3a1R,4R,6aR,7aS,10S,11S,11aS,11bR)-1,2,3a,4,10,11-Hexahydroxy-3,8,11a-trimethyl-1,2,3,3a,4,6a,7,7a,10,11,11a,11b-dodecahydro-5H-3,3a1-(epoxymethano)dibenzo[de,g]chromen-5-one

Bruceine E, 10 mM in DMSO

21586-90-3