ChemicalBook > CAS DataBase List > R 715
R 715
- Product Name
- R 715
- CAS No.
- 185052-09-9
- Chemical Name
- R 715
- Synonyms
- R 715;L-Isoleucine, N2-acetyl-L-lysyl-L-arginyl-L-prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-3-(2-naphthalenyl)-D-alanyl-
- CBNumber
- CB21346727
- Molecular Formula
- C57H81N13O12
- Formula Weight
- 1140.33
- MOL File
- 185052-09-9.mol
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R 715 Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- Desiccate at -20°C
- pka
- 3.35±0.10(Predicted)
- form
- Powder
- color
- White to off-white
- Water Solubility
- Soluble to 5 mg/ml in water
- Sequence
- Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-{d-βNal}-Ile
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N-Bromosuccinimide Price
Tocris
- Product number
- 3407
- Product name
- R715
- Packaging
- 1
- Price
- $244
- Updated
- 2021/12/16
Usbiological
- Product number
- 256396
- Product name
- R 715
- Packaging
- 1mg
- Price
- $495
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- BRS0000674
- Product name
- R 715
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $733.72
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B5420
- Product name
- R715
- Packaging
- 1mg
- Price
- $354
- Updated
- 2021/12/16
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R 715 Chemical Properties,Usage,Production
Description
Potent and selective bradykinin B1receptor antagonist (pA2= 8.49). Displays no activity at B2receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Metabolically stable.
Uses
R715 is a selective bradykinin B1 receptor antagonist. R715 significantly attenuates the hyperalgesic effect developed in Streptozotocin(HY-13753)-diabetic mice[1].
storage
Store at -20°C
References
[1] Gabra BH, et al. Beneficial effect of chronic treatment with the selective bradykinin B1 receptor antagonists, R-715 and R-954, in attenuating streptozotocin-diabetic thermal hyperalgesia in mice. Peptides. 2003;24(8):1131-1139. DOI:10.1016/j.peptides.2003.06.003
R 715 Preparation Products And Raw materials
Raw materials
Preparation Products
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R 715 Suppliers
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