ChemicalBook > CAS DataBase List > kaempferol-3-O-galactoside

kaempferol-3-O-galactoside

Product Name: kaempferol-3-O-galactoside
CAS No.: 23627-87-4
Chemical Name: kaempferol-3-O-galactoside
Synonyms: Trifolin;Trifolioside;Trifolin【glycoside】;Kaempferol 3-galactoside;kaempferol-3-O-galactoside;kaempferol3-O-β-D-galactoside;Kaempferol 3-galactopyranoside;kaempferol 3-O-beta-D-galactoside;Kaempferol 3-O-β-D-galactopyranoside;Kaempferol 3-O-β-D-galactopyranoside, 10 mM in DMSO
CBNumber: CB21358214
Molecular Formula: C21H20O11
Formula Weight: 448.38
MOL File: 23627-87-4.mol

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kaempferol-3-O-galactoside Property

Melting point:: 245-246℃
Boiling point:: 823.2±65.0 °C(Predicted)
Density: 1.79±0.1 g/cm3 (20 ºC 760 Torr)
storage temp.: -20°C
solubility: Ethanol: soluble
form: A solid
pka: 6.20±0.40(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H350May cause cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Usbiological

Product number: 301073
Product name: Trifolin
Packaging: 20mg
Price: $665
Updated: 2021/12/16

Arctom

Product number: AS003917
Product name: Kaempferol-3-O-Galactoside
Purity: ≥98%
Packaging: 5mg
Price: $282
Updated: 2021/12/16

Arctom

Product number: CFN92079
Product name: Kaempferol-3-O-galactoside
Packaging: 5mg
Price: $298
Updated: 2021/12/16

Crysdot

Product number: CD32001884
Product name: Trifolin
Purity: 95+%
Packaging: 5mg
Price: $1080
Updated: 2021/12/16

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kaempferol-3-O-galactoside Chemical Properties,Usage,Production

Uses

Kaempferol 3-O-β-D-galactopyranoside (Trifolin) is an orally active flavonoid derivative that can be found in the aerial parts of Consolida oliverana. Kaempferol 3-O-β-D-galactopyranoside exhibits antitumor and cardioprotective effects[1][2][3].

Definition

ChEBI: A beta-D-galactoside compound with a 4',5,7-trihydroxychromen-3-yl group at the anomeric position.

in vivo

Kaempferol 3-O-β-D-galactopyranoside (0.1–10.0 mg/kg, p.o., once daily for 4 weeks) improves cardiac function and reduces cardiomyocyte apoptosis in Angiotensin II (AngII) (HY-13948)-induced hypertensive cardiac injury C57BL/6 mice model^[3].

Animal Model:	Angiotensin II (AngII) (HY-13948)-induced hypertensive cardiac injury C57BL/6 mice model^[3]
Dosage:	0.1, 1.0, and 10.0 mg/kg
Administration:	Oral gavage (p.o.), once daily for 4 weeks
Result:	Improved left ventricular ejection fraction (LVEF) and fractional shortening (LVFS). Alleviated inflammatory cell infiltration and pathological damage in cardiac tissue. Reduced cardiomyocyte apoptosis and regulated Bax, Bcl-2, and cleaved caspase-3 protein expression

References

[1] da Silva I, et al. Structure determination of monohydrated trifolin (kaempferol 3-O-β-D-galactopyranoside) from laboratory powder diffraction data. J Pharm Sci. 2011;100(4):1588-1593. DOI:10.1002/jps.22379
[2] Kim MJ, et al. Trifolin induces apoptosis via extrinsic and intrinsic pathways in the NCI-H460 human non-small cell lung-cancer cell line. Phytomedicine. 2016 Sep 15;23(10):998-1004. DOI:10.1016/j.phymed.2016.05.009
[3] Zhang F, et al. Trifolin Attenuates Hypertension-Mediated Cardiac Injury by Inhibiting Cardiomyocyte Apoptosis: Mechanistic Insights and Therapeutic Potential. Eur J Pharmacol. 2024 Nov 9:177125. DOI:10.1016/j.ejphar.2024.177125

kaempferol-3-O-galactoside Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from kaempferol-3-O-galactoside manufacturers

Career Henan Chemical Co

Product: kaempferol-3-O-galactoside 23627-87-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

23627-87-4, kaempferol-3-O-galactosideRelated Search:

MOSLOFLAVONE Phlorizin dihydrate Hyperoside Kaempferol-3-O-(2,6-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside KAEMPFEROL-3-GLUCURONIDE KaeMpferol 7-O-rhaMnoside KaeMpferol-4'-O-β-D-glucopyranoside 7-[[2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-3,5-dihydroxy-2-(4-hydroxyphenyl)-4H-benzopyran-4-one Kaempferol 3-neohesperidoside KAEMPFEROL-7-O-GLUCOSIDE MEDICAGOL PONCIRIN Quercetin-7-O-β-D-glucopyranoside Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) GARDENIN B 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one 4',5-DIHYDROXY-7-METHOXYFLAVONE hydroxygenkwanin

kaempferol-3-O-galactoside

2-(4-Hydroxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one

3-(β-D-Galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Kaempferol 3-galactopyranoside

Kaempferol 3-galactoside

Trifolin【glycoside】

Trifolin

kaempferol 3-O-beta-D-galactoside

Trifolioside

4H-1-Benzopyran-4-one,3-(b-D-galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-

kaempferol3-O-β-D-galactoside

Kaempferol 3-O-β-D-galactopyranoside

Trifolin,Inhibitor,inhibit,Kaempferol 3 O β D galactopyranoside,Kaempferol 3OβDgalactopyranoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-chromen-4-one

4H-1-Benzopyran-4-one, 3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-

5,7-Dihydroxy-2-(4-hydroxyphenyl)-3-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

Kaempferol 3-O-β-D-galactopyranoside, 10 mM in DMSO

23627-87-4