ChemicalBook > CAS DataBase List > hamaudol
hamaudol
- Product Name
- hamaudol
- CAS No.
- 735-46-6
- Chemical Name
- hamaudol
- Synonyms
- hamaudol;Inhibitor,COX,Hamaudol,Cyclooxygenase,inhibit;(S)-3,5-Dihydroxy-2,2,8-trimethyl-3,4-dihydro-2H,6H-pyrano[3,2-g]chromen-6-one;(S)-3,4-Dihydro-3β,5-dihydroxy-2,2,8-trimethyl-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one;2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 3,4-dihydro-3,5-dihydroxy-2,2,8-trimethyl-, (3S)-
- CBNumber
- CB21363984
- Molecular Formula
- C15H16O5
- Formula Weight
- 276.28
- MOL File
- 735-46-6.mol
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hamaudol Property
- Melting point:
- 197.0-197.5 °C
- Boiling point:
- 464.7±45.0 °C(Predicted)
- Density
- 1.336±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- pka
- 6.77±0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0100499
- Product name
- Hamaudol
- Packaging
- 5mg
- Price
- $336
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0100499
- Product name
- Hamaudol
- Packaging
- 10mg
- Price
- $571
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb594459
- Product name
- Hamaudol
- Packaging
- 20mg
- Price
- $591.6
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb594459
- Product name
- Hamaudol
- Packaging
- 100mg
- Price
- $1757.8
- Updated
- 2021/12/16
AK Scientific
- Product number
- 1210CB
- Product name
- Hamaudol
- Packaging
- 500mg
- Price
- $4775
- Updated
- 2021/12/16
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hamaudol Chemical Properties,Usage,Production
Definition
ChEBI: Hamaudol is a member of chromenes.
Biological Activity
Hamaudol is a chromone isolated from Saposhnikovia divaricata. It has obvious inhibitory ability on the activities of cyclooxygenase (COX)-1 and COX-2 with IC50 values of 0.30 and 0.57 mM, respectively, and has potent analgesic and anti-inflammatory effects.
in vivo
Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency.
< b>
target
| COX-1 < span> 0.3 mM (IC 50 ) | COX-2 0.57 mM (IC 50 ) |
hamaudol Preparation Products And Raw materials
Raw materials
Preparation Products
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