ChemicalBook > CAS DataBase List > H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2

H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2

Product Name
H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2
CAS No.
209006-18-8
Chemical Name
H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2
Synonyms
PRL-2915;H-Phe(4-Cl)-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2;H-P-CHLORO-PHE-D-CYS-β-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2;H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2;H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2;H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 (Disulfide bond);H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 (Disulfide bond);{Phe<4-Cl>}-{d-Cys}-{β-Ala<3-Py>}-{d-Trp}-Lys-{Val<3-Me>}-Cys-{2-Nal}-NH2(Disulfide bond);H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2, (DISULFIDE BOND);H-p-Chloro-Phe-D-Cys-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2（(Disulfide bridge:DCys2-Cys7)）
CBNumber
CB2137258
Molecular Formula
C59H71ClN12O8S2
Formula Weight
1175.85
MOL File
209006-18-8.mol
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H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2 Property

Boiling point:
1507.0±65.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
pka
12.65±0.70(Predicted)
form 
Solid
color 
White to off-white
Sequence
{Phe<4-Cl>}-{d-Cys}-{β-Ala<3-Py>}-{d-Trp}-Lys-{Val<3-Me>}-Cys-{2-Nal}-NH2(Disulfide bond)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC109706
Product name
H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)
Packaging
500ug
Price
$145
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109706
Product name
H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)
Packaging
1mg
Price
$251
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109706
Product name
H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)
Packaging
2mg
Price
$427
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0010192
Product name
H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2
Purity
95.00%
Packaging
5MG
Price
$500.74
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC109706
Product name
H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)
Packaging
5mg
Price
$854
Updated
2021/12/16
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H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2 Chemical Properties,Usage,Production

Uses

PRL 2915 is a potent human somatostatin subtype 2 receptor (hsst2) antagonist with a Ki of 12 nM[1].

IC 50

hsst2: 12 nM (Ki); hsst3: 100 nM (Ki); hsst5: 520 nM (Ki); hsst4: 895 nM (Ki); hsst1: >1000 nM (Ki); hsst2: 1.8 nM (IC50, rat antagonist bioassay versus somatostatin); rat urotensin II receptor: 293 nM (Ki); human urotensin II receptor: 562 nM (Ki)

References

[1] Hocart SJ, et al. Highly potent cyclic disulfide antagonists of somatostatin. J Med Chem. 1999 Jun 3;42(11):1863-71. DOI:10.1021/jm9806289
[2] Rossowski WJ, et al. Human urotensin II-induced aorta ring contractions are mediated by protein kinase C, tyrosine kinases and Rho-kinase: inhibition by somatostatin receptor antagonists. Eur J Pharmacol. 2002 Mar 8;438(3):159-70. DOI:10.1016/s0014-2999(02)01341-9

H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2 Suppliers

China 27 United Kingdom 1 United States 2 Global 30
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
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United States
ProdList
12952
Advantage
65
Chem-Impex International, Inc.
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209006-18-8, H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2Related Search:

L-TERT-LEUCINE METHYLAMIDE H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2

  • PRL-2915
  • H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2
  • H-P-CHLORO-PHE-D-CYS-BETA-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2, (DISULFIDE BOND)
  • H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2
  • H-Phe(4-Cl)-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2
  • H-p-Chloro-Phe-D-Cys-b-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 trifluoroacetate salt (Disulfide bond)
  • H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 (Disulfide bond)
  • L-Alaninamide, 4-chloro-L-phenylalanyl-D-cysteinyl-3-(3-pyridinyl)-L-alanyl-D-tryptophyl-L-lysyl-3-methyl-L-valyl-L-cysteinyl-3-(2-naphthalenyl)-, cyclic (2→7)-disulfide
  • H-P-CHLORO-PHE-D-CYS-β-(3-PYRIDYL)-ALA-D-TRP-LYS-TBU-GLY-CYS-2-NAL-NH2
  • H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2 (Disulfide bond)
  • H-p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH? trifluoroacetate salt (Disulfide bond)
  • H-p-Chloro-Phe-D-Cys-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH2（(Disulfide bridge:DCys2-Cys7)）
  • {Phe<4-Cl>}-{d-Cys}-{β-Ala<3-Py>}-{d-Trp}-Lys-{Val<3-Me>}-Cys-{2-Nal}-NH2(Disulfide bond)
  • p-Chloro-Phe-D-Cys-β-(3-pyridyl)-Ala-D-Trp-Lys-tBu-Gly-Cys-2-Nal-NH? trifluoroacetate salt (Disulfide bond)
  • 209006-18-8
  • C59H71ClN12O8S2