4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene

Product Name: 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
CAS No.: 112241-19-7
Chemical Name: 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene
Synonyms: 4-Succinimidyloxycarbonyl-α-Methyl-α-(2-Pyridyldithio)toluene;4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene;2,5-Dioxopyrrolidin-1-yl 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate;2,5-dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulfaneyl)ethyl)benzoate;Benzoic acid, 4-[1-(2-pyridinyldithio)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB21374227
Molecular Formula: C18H16N2O4S2
Formula Weight: 388.46
MOL File: 112241-19-7.mol

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4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Property

storage temp.: 2-8°C
solubility: Soluble in DMSO
form: Solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 803472
Product name: SMPT (4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene)
Packaging: 50MG
Price: $484
Updated: 2023/06/20

TRC

Product number: S688098
Product name: 4-Succinimidyloxycarbonyl-α-methyl-α-(2-pyridyldithio)toluene
Packaging: 10mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-0103518
Product name: SMPT
Packaging: 100mg
Price: $460
Updated: 2021/12/16

Abosyn

Product number: 40-0198
Product name: 2,5-Dioxopyrrolidin-1-yl4-(1-(pyridin-2-yldisulfanyl)ethyl)benzoate
Purity: >95%
Packaging: 250mg
Price: $590
Updated: 2021/12/16

Alichem

Product number: 112241197
Product name: 4-Succinimidyloxycarbonyl-alpha-methyl-alpha-(2-pyridyldithio)toluene
Packaging: 1g
Price: $1088.78
Updated: 2021/12/16

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4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Chemical Properties,Usage,Production

General Description

SMPT is a heterobifunctional sulfhydryl- and amine-reactive cross-linker. SMPT is used often for conjugating a toxin molecule to a monoclonal antibody directed against a cell-surface antigen. These immunotoxins produced with SMPT are highly potent as the cleavable disulfide imparts increased cytotoxicity compared to conjugates without a cleavable bond, such as those produced with SPDP. Also, next to the pyridine-2-thione in the spacer arm are a benzene ring and a methyl group adjacent to a carbon that hinders the disulfide bond, allowing exceptional conjugate stability in vivo. SMPT has the added benefit of being more stable to hydrolysis in aqueous solutions than other NHS cross-linkers.

4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Preparation Products And Raw materials

Raw materials

Preparation Products

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4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene Suppliers

China 24 South Korea 1 United States 4 Global 29

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View Lastest Price from 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: SMPT 112241-19-7
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-21

Hangzhou Huarong Pharm Co., Ltd.

Product: SMPT 112241-19-7
Price: US $0.00-0.00/mg
Min. Order: 50mg
Purity: 99%
Supply Ability: 100KG
Release date: 2021-09-15

112241-19-7, 4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)tolueneRelated Search:

4-succinimidyloxycarbonyl-alpha-methyl-alpha(2-pyridyldithio)toluene

4-Succinimidyloxycarbonyl-α-Methyl-α-(2-Pyridyldithio)toluene

2,5-Dioxopyrrolidin-1-yl 4-[1-(pyridin-2-yldisulfanyl)ethyl]benzoate

2,5-dioxopyrrolidin-1-yl 4-(1-(pyridin-2-yldisulfaneyl)ethyl)benzoate

Benzoic acid, 4-[1-(2-pyridinyldithio)ethyl]-, 2,5-dioxo-1-pyrrolidinyl ester

112241-19-7