ambuic acid
- Product Name
- ambuic acid
- CAS No.
- 340774-69-8
- Chemical Name
- ambuic acid
- Synonyms
- ambuic acid;Ambuic acid, antibiotic agent;(2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid;2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
- CBNumber
- CB21380277
- Molecular Formula
- C19H26O6
- Formula Weight
- 350.41
- MOL File
- 340774-69-8.mol
ambuic acid Property
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble; Ethanol: soluble; Methanol: soluble
- form
- A solid
- color
- Off-white
N-Bromosuccinimide Price
- Product number
- 27483
- Product name
- Ambuic Acid
- Packaging
- 500μg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 27483
- Product name
- Ambuic Acid
- Packaging
- 1mg
- Price
- $228
- Updated
- 2024/03/01
- Product number
- 044498
- Product name
- Ambuic acid
- Packaging
- 250ug
- Price
- $303
- Updated
- 2021/12/16
- Product number
- 5106CS
- Product name
- Ambuicacid
- Packaging
- 1mg
- Price
- $351
- Updated
- 2021/12/16
- Product number
- INB0009801
- Product name
- AMBUIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $519.65
- Updated
- 2021/12/16
ambuic acid Chemical Properties,Usage,Production
Description
Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi, including F. solani, H. sativum, and C. gramineum, but not P. oryzae, R. solani, or B. cinerea. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 μg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.
storage
+4°C
ambuic acid Preparation Products And Raw materials
Raw materials
Preparation Products
ambuic acid Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77