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ambuic acid

Product Name
ambuic acid
CAS No.
340774-69-8
Chemical Name
ambuic acid
Synonyms
ambuic acid;Ambuic acid, antibiotic agent;(2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid;2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
CBNumber
CB21380277
Molecular Formula
C19H26O6
Formula Weight
350.41
MOL File
340774-69-8.mol
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ambuic acid Property

storage temp. 
Store at -20°C
solubility 
DMSO: soluble; Ethanol: soluble; Methanol: soluble
form 
A solid
color 
Off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27483
Product name
Ambuic Acid
Packaging
500μg
Price
$120
Updated
2024/03/01
Cayman Chemical
Product number
27483
Product name
Ambuic Acid
Packaging
1mg
Price
$228
Updated
2024/03/01
Usbiological
Product number
044498
Product name
Ambuic acid
Packaging
250ug
Price
$303
Updated
2021/12/16
AK Scientific
Product number
5106CS
Product name
Ambuicacid
Packaging
1mg
Price
$351
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0009801
Product name
AMBUIC ACID
Purity
95.00%
Packaging
5MG
Price
$519.65
Updated
2021/12/16
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ambuic acid Chemical Properties,Usage,Production

Description

Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. It is active against P. ultimum (MIC = 7.5 μg/ml) and inhibits the growth of a variety of other phytopathogenic fungi, including F. solani, H. sativum, and C. gramineum, but not P. oryzae, R. solani, or B. cinerea. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 μg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.

storage

+4°C

ambuic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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ambuic acid Suppliers

BOC Sciences
Tel
16314854226; +16314854226
Email
inquiry@bocsci.com
Country
United States
ProdList
19741
Advantage
58
Abcam
Tel
--
Fax
--
Email
us.orders@abcam.com
Country
United States
ProdList
6000
Advantage
50
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80

340774-69-8, ambuic acidRelated Search:


  • ambuic acid
  • (2E)-4-[(1R,5R,6R)-3-(1E)-1-Hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid
  • 2-Butenoic acid, 4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-, (2E)-
  • Ambuic acid, antibiotic agent
  • 340774-69-8