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phycocyanobilin

Product Name: phycocyanobilin
CAS No.: 20298-86-6
Chemical Name: phycocyanobilin
Synonyms: Spirullina;phycocyanobilin;3(E)-Phycocyanobilin;Phycocyanobilin - PCB;Phycocyanobilin (Protein mixture);Phycocyanobilin (Microbial source);21H-Biline-8,12-dipropanoic acid, 18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-, (2R,3E)-;(2R,3E,4Z,10Z,15Z)-18-Ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid;-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethyl-3-methyl-5-oxo-pyrrol-2-yl)methylene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxo-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid;3-((Z)-2-((3-(2-Carboxyethyl)-5-((Z)-((R,E)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene)methyl)-4-methyl-1H-pyrrol-2-yl)methylene)-5-((Z)-(4-ethyl-3-methyl-5-oxo-1H-pyrrol-2(5H)-ylidene)methyl)-4-methyl-2H-pyrrol-3-yl)propanoic acid
CBNumber: CB21380404
Molecular Formula: C33H38N4O6
Formula Weight: 586.69
MOL File: 20298-86-6.mol

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phycocyanobilin Property

Boiling point:: 892.1±65.0 °C(Predicted)
Density: 1.31±0.1 g/cm3(Predicted)
pka: 4.47±0.10(Predicted)
form: Solid
color: Blue to dark blue

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Frontier Specialty Chemicals

Product number: P14137
Product name: Phycocyanobilin(microbialsource)
Purity: >95%
Packaging: 5mg
Price: $119
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: P14137
Product name: Phycocyanobilin(microbialsource)
Purity: >95%
Packaging: 25mg
Price: $432
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: P14137
Product name: Phycocyanobilin(microbialsource)
Purity: >95%
Packaging: 50mg
Price: $785
Updated: 2021/12/16

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phycocyanobilin Chemical Properties,Usage,Production

Uses

Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease[1][2][3].

in vivo

Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) shows antioxidant effects in type 2 diabetes mice^[3].

Animal Model:	Male C57BL/Ks J db/db mice, a rodent model for type 2 diabetes^[3]
Dosage:	15 mg/kg
Administration:	In diet for 2 weeks
Result:	Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF_2α levels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.

Enzyme inhibitor

This linear tetrapyrrole (FW = 559.64 g/mol) is a prosthetic group of blue, highly fluorescent photoreceptor pigments (phycocyanins) found in certain algae. It is soluble in water and polar organic solvents. Phycocyanins, found in Cyanophyta, are proteins, which typically contain three molecules of covalently bound phycocyanobilin per subunit. One molecule of phycocyanobilin is bound per molecule of allophycocyanin, found in Cyanophyta and Rhodophyta. Phycocyanins and their chromophore phycocyanobilin are peroxy radical scavengers and inhibits ONOO–- mediated biological effects. Target(s): cyclooxygenase-2, inhibited by C-phycocyanin and poorly by phycocyanobilin.

References

[1] Hirata T, et al. Antioxidant activities of phycocyanobilin prepared from Spirulina platensis. Journal of Applied Phycology, 2000, 12: 435-439.
[2] Matamoros BP, et al. Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease. J Biosci. 2021;46:42. PMID:34047285
[3] Zheng J, et al. Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R110-20. DOI:10.1152/ajpregu.00648.2011

phycocyanobilin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from phycocyanobilin manufacturers

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.

Product: Spirulina powder 20298-86-6
Price: US $17.00/KG
Min. Order: 1KG
Purity: 55% and 77%
Supply Ability: 1mt
Release date: 2020-09-07

Shaanxi Dideu Medichem Co. Ltd

Product: phycocyanobilin 20298-86-6
Price: US $1.00-1.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 800 tons
Release date: 2020-04-21

20298-86-6, phycocyanobilinRelated Search:

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phycocyanobilin

(2R,3E,4Z,10Z,15Z)-18-Ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid

3(E)-Phycocyanobilin

Phycocyanobilin (Microbial source)

Phycocyanobilin - PCB

Spirullina

21H-Biline-8,12-dipropanoic acid, 18-ethyl-3-ethylidene-1,2,3,19,22,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-, (2R,3E)-

-[2-[(Z)-[(5E)-3-(2-carboxyethyl)-5-[(4-ethyl-3-methyl-5-oxo-pyrrol-2-yl)methylene]-4-methyl-pyrrol-2-ylidene]methyl]-5-[(Z)-[(3E,4R)-3-ethylidene-4-methyl-5-oxo-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid

3-((Z)-2-((3-(2-Carboxyethyl)-5-((Z)-((R,E)-3-ethylidene-4-methyl-5-oxopyrrolidin-2-ylidene)methyl)-4-methyl-1H-pyrrol-2-yl)methylene)-5-((Z)-(4-ethyl-3-methyl-5-oxo-1H-pyrrol-2(5H)-ylidene)methyl)-4-methyl-2H-pyrrol-3-yl)propanoic acid

Phycocyanobilin (Protein mixture)

20298-86-6

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