BENAZEPRILAT

Product Name: BENAZEPRILAT
CAS No.: 86541-78-8
Chemical Name: BENAZEPRILAT
Synonyms: Cibacen;CGS-14831;BENAZEPRILAT;L-Tyrosine-d;Benazepril EP Imp C;Benazepril Impurity C;Benazepril Impurity 3;BENAZEPRILAT HCL HYDRATE;Benazepril EP Impurity C;Benazeprilat (CGS 14831)
CBNumber: CB2144780
Molecular Formula: C22H24N2O5
Formula Weight: 396.44
MOL File: 86541-78-8.mol

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BENAZEPRILAT Property

Melting point:: 270-272°C
alpha: D -200.5° (c = 1 in 3% aqueous NH4OH)
Boiling point:: 711.3±60.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer, Under Inert Atmosphere
solubility: Aqueous Base (Slightly), DMSO (Slightly)
form: Solid
pka: 2.17±0.10(Predicted)
color: White to Off-White
InChIKey: MADRIHWFJGRSBP-ROUUACIJSA-N
SMILES: N1(CC(O)=O)C2=CC=CC=C2CC[C@H](N[C@H](C(O)=O)CCC2=CC=CC=C2)C1=O
CAS DataBase Reference: 86541-78-8

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Safety

HS Code: 2933790002

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 1048641
Product name: Benazepril Related Compound C
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 50mg
Price: $1250
Updated: 2025/07/31

Cayman Chemical

Product number: 21796
Product name: Benazeprilat
Purity: ≥98%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 21796
Product name: Benazeprilat
Purity: ≥98%
Packaging: 5mg
Price: $286
Updated: 2024/03/01

Cayman Chemical

Product number: 21796
Product name: Benazeprilat
Purity: ≥98%
Packaging: 10mg
Price: $535
Updated: 2024/03/01

Usbiological

Product number: B1035-15
Product name: Benazeprilat
Packaging: 5mg
Price: $425
Updated: 2021/12/16

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BENAZEPRILAT Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Uses

Benazeprilat is a metabolite of Benazepril, which is used as an antihypertensive.

Definition

ChEBI: A benzazepine that is 1,3,4,5-tetrahydro-2H-1-benzazepin-2-one in which the hydrogen attached to the nitrogen is replaced by a carboxy methyl group and in which the 3-pro-S hydrogen is replaced by the amino roup of (2S)-2-amino-4-phenylbutanoic acid. An angiotensin-converting enzyme inhibitor, it is used as its monoester prodrug benazepril in the treatment of hypertension and heart failure.

in vivo

Benazeprilat (10 mg/kg, intravenous injection) and amlodipine (0.5 mg/kg, intravenous injection) in combination produce great hypotensive effect^[2].
Benazepril (0.7 mg/kg, oral) markedly influences the dynamics of systemic RAAS peptides, resulting in a substantial decrease in AII and ALD while increasing PRA and AI^[3].

Animal Model:	Male SHR (14-16 weeks of age, 250-350 g)^[2].
Dosage:	10 mg/kg
Administration:	I.V; once a day for 2 days.
Result:	Produced hypotensive effect.

Animal Model:	Beagle dogs (12.0-19.5 kg)^[3].
Dosage:	0.7 mg/kg
Administration:	P.O, once a day for 5 days.
Result:	Effected systemic RAAS peptides.

BENAZEPRILAT Preparation Products And Raw materials

Raw materials

Preparation Products

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BENAZEPRILAT Suppliers

Canada 3 China 90 Germany 1 India 7 United Kingdom 4 United States 22 Global 127

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Email: jkinfo@jkchemical.com
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Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
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Sinopharm Chemical Reagent Co,Ltd.

Tel: 86-21-63210123
Fax: 86-21-63290778 86-21-63218885
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Wisdom Pharmaceutical Co., Ltd.

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Fax: 0086-513-81292226
Email: l_xu@wisdompharma.com
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ProdList: 221
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Cato Research Chemicals Inc.

Tel: 020-81960175
Fax: +1-541-2553641
Email: min.he@cato-chem.com
Country: China
ProdList: 1955
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ChemStrong Scientific Co.,Ltd

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Email: sales@chem-strong.com
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ProdList: 18333
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Shanghai Kewel Chemical Co., Ltd.

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Email: greensnown@163.com
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BOC Sciences

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Email: info@bocsci.com
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Beijing Solarbio Science & Tecnology Co., Ltd.

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ProdList: 6338
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Hubei Yangxin Medical Technology Co., Ltd.

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Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 10000
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View Lastest Price from BENAZEPRILAT manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Benazepril EP Impurity C 86541-78-8
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-03-27

86541-78-8, BENAZEPRILATRelated Search:

CGP 14829A (S)-3-AMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid BENAZEPRIL-D5 HYDROCHLORIDE Benazepril-(17a) Benazepril-(S,R) BENAZEPRILAT-D5 Benazepril Impurity 1 (Benazepril Methyl Ester) S-ATBA Benazepril hydrochloride BENAZEPRILAT BENAZEPRIL-D5 Benazeprilat Acyl--D-glucuronide BENAZEPRIL TERT-BUTYL ESTER D5 Benazeprilat-d5 Acyl--D-glucuronide BENAZEPRIL RELATED COMPOUND A (15 MG) ((3R)-3-[[(1 R)-1 -(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMI-NO]-2,3,4,5-TETRAHYDRO-2-OXO-1 H-1 -BENZAZEPINE-1-ACETIC ACID, MONOHYDROCHLORIDE) BENAZEPRILAT MM(CRM STANDARD) BENAZEPRILAT MM BENAZEPRIL RELATED COMPOUND B (15 MG) ((3S)-3-[[(1 R)-1 -(ETHOXYCARBONYL)-3-PHENYLPROPYL]AMI-NO]-2,3,4,5-TETRAHYDRO-2-OXO-1 H-1 -BENZAZEPINE-1-ACETIC ACID, MONOHYDROCHLORIDE)

BENAZEPRILAT

BENAZEPRILAT HCL HYDRATE

Benazepril hydrochloride impurity C

Benazepril Impurity 3(Benazepril EP Impurity C)

(3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid

CGS-14831

Benazepril Related Compound C (50 mg) ((3S)-3-[[(1S)-1- carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-oxo- 1H-1-benzazepine]-1-acetic acid)

(3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]aMino-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine]-1-acetic acid

Benazepril Related CoMpound C

Cibacen

BENAZEPRILAT HYDROCHLORIDE HYDRATE

1H-1-Benzazepine-1-acetic acid, 3-(1S)-1-carboxy-3-phenylpropylamino-2,3,4,5-tetrahydro-2-oxo-, (3S)-

Benazepril Diacid (Benaz. EP Impurity C)

Benazepril Impurity C

Benazepril EP Imp C

Benazepril EP Impurity C

Benazepril EP Impurity C (Disodium Salt)

(S)-2-(((S)-1-(carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)amino)-4-phenylbutanoic acid

Benazepril EP Impurity C/ Benazepril Related Compund C (Benazeprilat)

Benazeprilat (CGS 14831)

BenazeprilatQ: What is Benazeprilat Q: What is the CAS Number of Benazeprilat Q: What is the storage condition of Benazeprilat Q: What are the applications of Benazeprilat

Benazepril Impurity 3

(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoic Acid

Benazepril Related Compound C ((3S)-3-[[(1S)-1-carboxy-3-phenylpropyl]amino-2,3,4,5-tetrahydro-2-ox (1048641)

Benazepril USP Related Compound C

L-Tyrosine-d

CGS14831|||CGS-14831|||CGS 14831

Benazepril EP Impurity C (Benazepril USP Related Compound C, Benazeprilat)

(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoi

Benazeprilat EP Impurity C

(2S)-2-[[(3S)-1-(Carboxymethyl)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-3-yl]amino]-4-phenylbutanoic Acid (Benazeprilat)

Benazepril Imp. C (EP): (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid

(3S)-3-[[(S)-1-Carboxy-3-phenylpropyl]amino]-2

5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid

86541-78-8

Intermediates & Fine Chemicals

Metabolites

Pharmaceuticals

Aromatics

Heterocycles

Metabolites & Impurities

Chiral Reagents