5-bromo-1-methyl-1,2,4-triazole
- Product Name
- 5-bromo-1-methyl-1,2,4-triazole
- CAS No.
- 16681-72-4
- Chemical Name
- 5-bromo-1-methyl-1,2,4-triazole
- Synonyms
- 5-BroMo-1-Methyl-1H-1,2,4-triazole;1-Methyl-5-bromo-1,2,4-triazole;5-bromo-1-methyl-1,2,4-triazole;1H-1,2,4-Triazole, 5-bromo-1-methyl-
- CBNumber
- CB21459593
- Molecular Formula
- C3H4BrN3
- Formula Weight
- 161.99
- MOL File
- 16681-72-4.mol
5-bromo-1-methyl-1,2,4-triazole Property
- Boiling point:
- 256℃
- Density
- 1.93
- Flash point:
- 109℃
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 0.98±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C3H4BrN3/c1-7-3(4)5-2-6-7/h2H,1H3
- InChIKey
- ZYLIOXAULQKGII-UHFFFAOYSA-N
- SMILES
- N1(C)C(Br)=NC=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CBR01745
- Product name
- 5-Bromo-1-methyl-1H-1,2,4-triazole
- Purity
- AldrichCPR
- Packaging
- 1g
- Price
- $497
- Updated
- 2025/07/31
- Product number
- B697848
- Product name
- 5-Bromo-1-methyl-1H-1,2,4-triazole
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FB126981
- Product name
- 5-Bromo-1-methyl-1H-1,2,4-triazole
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- FB126981
- Product name
- 5-Bromo-1-methyl-1H-1,2,4-triazole
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 3H32-9-DA
- Product name
- 5-Bromo-1-methyl-1H-1,2,4-triazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
5-bromo-1-methyl-1,2,4-triazole Chemical Properties,Usage,Production
Synthesis
6086-21-1
16681-72-4
General procedure for the synthesis of 5-bromo-1-methyl-1H-1,2,4-triazole from 1-methyl-1H-1,2,4-triazole: 1.6 M n-BuLi (8.70 mL, 13.86 mmol) was slowly added to a mixed solution of 1-methyl-1H-1,2,4-triazole (1.0 mL, 13.20 mmol) and THF (100 mL) at -78 °C. 13.86 mmol). After 45 min of reaction, 1,2-dibromo-1,1,2,2-tetrafluoroethane (1.76 mL, 14.52 mmol) was added, and then the reaction mixture was slowly warmed to room temperature and stirring was continued for 2 hours. After completion of the reaction, the reaction solution was diluted with EtOAc (200 mL), washed sequentially with water (150 mL) and brine (150 mL), the organic phase was dried with MgSO4, filtered and concentrated to afford 5-bromo-1-methyl-1H-1,2,4-triazole (1.37 g, 8.46 mmol, 64% yield). The product was confirmed by 1H NMR (CDCl3): δ 3.82 (s, 3H), 7.78 (s, 1H). LC/MS analysis showed that the m/z calculated value [C3H4BrN3(M+H)+] was 162.0 and the measured value was 161.9.
References
[1] Patent: WO2006/102194, 2006, A1. Location in patent: Page/Page column 117-118
5-bromo-1-methyl-1,2,4-triazole Preparation Products And Raw materials
Raw materials
Preparation Products
5-bromo-1-methyl-1,2,4-triazole Suppliers
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- --
- Fax
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- sales@ajchem.in
- Country
- India
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- 6100
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View Lastest Price from 5-bromo-1-methyl-1,2,4-triazole manufacturers
- Product
- 5-bromo-1-methyl-1,2,4-triazole 16681-72-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 5-bromo-1-methyl-1,2,4-triazole 16681-72-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 5-bromo-1-methyl-1,2,4-triazole 16681-72-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000Kgs
- Release date
- 2020-01-09