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QUASSIN

Product Name
QUASSIN
CAS No.
76-78-8
Chemical Name
QUASSIN
Synonyms
Balsam;QUASSIN;Nsc 36342;Quassin-RM;Alloquassin;4-epiquassin;Quassin (>QUASSINPOWDER;Quassin (~90%);Quassin (>95%)
CBNumber
CB2147903
Molecular Formula
C22H28O6
Formula Weight
388.45
MOL File
76-78-8.mol
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QUASSIN Property

Melting point:
222°
alpha 
D20 +34.5° (c = 5.09 in CHCl3)
Boiling point:
586.3±50.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
optical activity
+34.520 (c 5.09, CHCl3)
InChIKey
IOSXSVZRTUWBHC-LBTVDEKVSA-N
SMILES
C1(=O)[C@]2([C@](C[C@@]3([C@@]4([C@@]2(C(=O)C(OC)=C(C)[C@]4([H])CC(=O)O3)[H])C)[H])([H])[C@H](C)C=C1OC)C
LogP
2.220 (est)
EPA Substance Registry System
Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy- (76-78-8)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
Q509400
Product name
Quassin(MixtureofQuassin,IsoquassinandNeoquassin)
Packaging
2.5mg
Price
$165
Updated
2021/12/16
TRC
Product number
Q509400
Product name
Quassin(MixtureofQuassin,IsoquassinandNeoquassin)
Packaging
25mg
Price
$1320
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ66238
Product name
Quassin - isomeric mixture of isoquassin, neoquassin and quassin
Packaging
25mg
Price
$1500
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ143433
Product name
Quassin - 92%
Packaging
100mg
Price
$800
Updated
2021/12/16
Biosynth Carbosynth
Product number
FQ143433
Product name
Quassin - 92%
Packaging
50mg
Price
$500
Updated
2021/12/16
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QUASSIN Chemical Properties,Usage,Production

Uses

Quassin is a naturally occurring extract from quassia trees and is used in traditional chinese medicine for its antiulcerogenic properties. Quassin have also been used as an additive in soft drinks.

Definition

ChEBI: Quassin is a triterpenoid.

in vivo

Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats[1].

Animal Model:35 females albino rats (150-170 g)[1]
Dosage:0.1 mg/kg, 1.0 mg/kg and 2.0 mg/kg
Administration:Oral administration; daily; for 60 days
Result:There was a significant decrease in the weight of the ovary and uterus in all the groups relative to the control. There was also a significant decrease in serum estrogen levels in quassin treated rats.

IC 50

Plasmodium

QUASSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from QUASSIN manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
QUASSIN 76-78-8
Price
US $0.10/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10
Release date
2024-08-04
Shaanxi Haibo Biotechnology Co., Ltd
Product
QUASSIN 76-78-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-08-21

76-78-8, QUASSINRelated Search:


  • Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy-
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  • (3As,6ar,7as,8S,11as,11bs,11cs)-1,3A,4,5,6A,7,7A,8,11,11A,11B,11C-dodecahydro-2,10-dimethoxy-3,8,11A,11C-tetramethyldibenzo(de,G)chromene-1,5,11-trione
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  • Einecs 200-985-9
  • Nsc 36342
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  • Quassin (>95%)
  • Anti-infection
  • Quassin-RM
  • 76-78-8
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  • C22H28O6