2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine
- Product Name
- 2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine
- CAS No.
- 17775-01-8
- Chemical Name
- 2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine
- Synonyms
- 3,4-Dihydro-2H-benzo[f][1,4]oxazepine;2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine;2,3,4,5-tetrahydro-1,4-benzoxazepine(SALTDATA: FREE)
- CBNumber
- CB21482139
- Molecular Formula
- C9H11NO
- Formula Weight
- 149.19
- MOL File
- 17775-01-8.mol
2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T796513
- Product name
- 2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FD151708
- Product name
- 3,4-Dihydro-2H-benzo[f][1,4]oxazepine
- Packaging
- 25mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FD151708
- Product name
- 3,4-Dihydro-2H-benzo[f][1,4]oxazepine
- Packaging
- 50mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FD151708
- Product name
- 3,4-Dihydro-2H-benzo[f][1,4]oxazepine
- Packaging
- 100mg
- Price
- $250
- Updated
- 2021/12/16
- Product number
- FD151708
- Product name
- 3,4-Dihydro-2H-benzo[f][1,4]oxazepine
- Packaging
- 250mg
- Price
- $400
- Updated
- 2021/12/16
2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine Chemical Properties,Usage,Production
Synthesis
703-51-5
17775-01-8
B. Synthesis of 2,3,4,5-tetrahydrobenzo[f][1,4]oxazepines. Lithium aluminum hydride (0.85 g, 22 mmol) was added batchwise to a solution of 3,4-dihydro-2H-benzo[f][1,4]oxazepin-5-one (1.22 g, 7.48 mmol) in tetrahydrofuran (THF, 20 mL) at 0 °C. The reaction mixture was heated to reflux for 24 h and subsequently cooled to room temperature. Water (0.85 mL), 15% aqueous sodium hydroxide solution (0.85 mL) and water (2.55 mL) were added sequentially and slowly dropwise with continuous stirring. The insoluble salt was removed by filtration and the filtrate was concentrated to give the target product 2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine (0.80 g, 72% yield). Thin layer chromatography (TLC) analysis (silica gel plate, unfolding agent: ethyl acetate) showed an Rf value of 0.14. Nuclear magnetic resonance hydrogen spectroscopy (1H NMR, 500 MHz, CDCl3) data: δ 7.19-7.12 (m, 2H), 7.03-6.97 (m, 2H), 4.04 (t, J = 4.5 Hz, 2H), 3.96 (s, 2H). 3.23 (t, J = 4.5 Hz, 2H), (one hydrogen signal not observed).
References
[1] Patent: US2005/38032, 2005, A1. Location in patent: Page/Page column 21
[2] Journal of Medicinal Chemistry, 1996, vol. 39, # 18, p. 3539 - 3546
2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine Preparation Products And Raw materials
Raw materials
Preparation Products
2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine Suppliers
- Tel
- --
- Fax
- --
- enamine@enamine.net
- Country
- Ukraine
- ProdList
- 6216
- Advantage
- 67
View Lastest Price from 2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine manufacturers
- Product
- 2,3,4,5-Tetrahydrobenzo[f][1,4]oxazepine 17775-01-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2020-03-23