ChemicalBook > CAS DataBase List > 5-Chloro-2-iodopyrimidine

5-Chloro-2-iodopyrimidine

Product Name
5-Chloro-2-iodopyrimidine
CAS No.
874676-81-0
Chemical Name
5-Chloro-2-iodopyrimidine
Synonyms
5-Chloro-2-iodopyrimidine;Pyrimidine, 5-chloro-2-iodo-;5-Chloro-2-iodopyrimidine 97%;5-Chloro-2-iodopyrimidine ISO 9001:2015 REACH
CBNumber
CB21483439
Molecular Formula
C4H2ClIN2
Formula Weight
240.43
MOL File
874676-81-0.mol
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5-Chloro-2-iodopyrimidine Property

Boiling point:
316.6±34.0 °C(Predicted)
Density 
2.187±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka
-2.56±0.22(Predicted)
form 
Powder
color 
White
Water Solubility 
Slightly soluble in water.
Sensitive 
Light Sensitive
InChI
InChI=1S/C4H2ClIN2/c5-3-1-7-4(6)8-2-3/h1-2H
InChIKey
BWDLBDLGVMLSCS-UHFFFAOYSA-N
SMILES
C1(I)=NC=C(Cl)C=N1
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Safety

Hazard Codes 
Xn
Risk Statements 
22
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00017
Product name
5-Chloro-2-iodopyrimidine
Purity
Aldrich
Packaging
1g
Price
$174
Updated
2024/03/01
Alfa Aesar
Product number
H64185
Product name
5-Chloro-2-iodopyrimidine, 98%
Packaging
1g
Price
$52.4
Updated
2021/12/16
Alfa Aesar
Product number
H64185
Product name
5-Chloro-2-iodopyrimidine, 98%
Packaging
5g
Price
$208
Updated
2021/12/16
Alfa Aesar
Product number
H64185
Product name
5-Chloro-2-iodopyrimidine, 98%
Packaging
250mg
Price
$17.8
Updated
2021/12/16
TRC
Product number
C381668
Product name
5-Chloro-2-iodopyrimidine
Packaging
10mg
Price
$45
Updated
2021/12/16
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5-Chloro-2-iodopyrimidine Chemical Properties,Usage,Production

Description

5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It is a halogenated derivative of pyrimidine and has a molecular formula of C4H2ClIN2. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry.

Uses

Useful Intermediate for organic synthesis and pharmaceutical.

Preparation

A flask was charged with 57% HI (48 ml) and then cooled to 0°C in an ice-salt mixture. Dichloropyrimidine (6 g) was added to the mixture. After 4h, the obtained yellow suspension was treated carefully with K2CO3 solution (32 g, 60 ml), and the pale yellow solid was collected by filtration. The solid was washed with water and dried to give compound 5-Chloro-2-iodopyrimidine.

Application

As a chemical intermediate used in the pharmaceutical and agrochemical industriesIt, 5-Chloro-2-iodopyrimidine is commonly used as a building block in the synthesis of biologically active molecules, such as kinase inhibitors, antiviral agents, and herbicides.

Origin

5-Chloro-2-iodopyrimidine was discovered by  chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules.

5-Chloro-2-iodopyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Chloro-2-iodopyrimidine Suppliers

Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 5-Chloro-2-iodopyrimidine manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-Chloro-2-iodopyrimidine 874676-81-0
Price
US $36.00-1.10/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Dideu Industries Group Limited
Product
5-Chloro-2-iodopyrimidine 874676-81-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06
Career Henan Chemical Co
Product
5-Chloro-2-iodopyrimidine 874676-81-0
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000KGS
Release date
2020-01-09

874676-81-0, 5-Chloro-2-iodopyrimidineRelated Search:


  • 5-Chloro-2-iodopyrimidine
  • 5-Chloro-2-iodopyrimidine 97%
  • Pyrimidine, 5-chloro-2-iodo-
  • 5-Chloro-2-iodopyrimidine ISO 9001:2015 REACH
  • 874676-81-0
  • C4H2ClIN
  • C4H2ClIN2
  • Heterocycle-Pyrimidine series
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Heterocyclic Compounds
  • Pyrimidine