(S)-3-PIPERIDINE-3-CARBOXYLIC ACID
- Product Name
- (S)-3-PIPERIDINE-3-CARBOXYLIC ACID
- CAS No.
- 851956-01-9
- Chemical Name
- (S)-3-PIPERIDINE-3-CARBOXYLIC ACID
- Synonyms
- L(+)-NIPECOTIC ACID HCL;(S)-(+)-Nipecotic acid HCl;L(+)-nipecotic acid hydrochloride;(S)-3-PIPERIDINE-3-CARBOXYLIC ACID;(3S)-3-Piperidinecarboxylic acid hydrochloride;(3S)-piperidine-3-carboxylic acid hydrochloride;(S)-3-Piperidine-3-CarboxylicAcid hydrochloride;(3S)-3-Piperidinecarboxylic acid hydrochloride salt
- CBNumber
- CB21502811
- Molecular Formula
- C6H12ClNO2
- Formula Weight
- 165.62
- MOL File
- 851956-01-9.mol
(S)-3-PIPERIDINE-3-CARBOXYLIC ACID Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P000106143
- Product name
- (S)-Piperidine-3-carboxylic acid hydrochloride
- Purity
- 98%
- Packaging
- 250mg
- Price
- $7
- Updated
- 2021/12/16
- Product number
- P000106143
- Product name
- (S)-Piperidine-3-carboxylic acid hydrochloride
- Purity
- 98%
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- AS48700
- Product name
- (S)-Piperidine-3-carboxylic acid hydrochloride
- Purity
- 98% ee
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- P000106143
- Product name
- (S)-Piperidine-3-carboxylic acid hydrochloride
- Purity
- 98%
- Packaging
- 5g
- Price
- $59
- Updated
- 2021/12/16
- Product number
- P000106143
- Product name
- (S)-Piperidine-3-carboxylic acid hydrochloride
- Purity
- 98%
- Packaging
- 10g
- Price
- $106
- Updated
- 2021/12/16
(S)-3-PIPERIDINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
88495-54-9
851956-01-9
The general steps for the synthesis of (S)-piperidine-3-carboxylic acid hydrochloride from N-Boc-(S)-3-carboxylic acid piperidine are as follows: Step 1. Preparation of (3S)-piperidine-3-carboxylic acid hydrochloride (3S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid (4.0 g, 0.017 mol) was dissolved in dichloromethane (10 mL, 0.2 mol), and a 1,4-dioxane solution (30 mL) of 4.0 M hydrogen chloride was added. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the volatiles were removed by vacuum distillation to give (3S)-piperidine-3-carboxylic acid hydrochloride in quantitative yield. The crude product did not require further purification and could be used directly in subsequent steps.LCMS analysis showed m/z 166.2 (M + H)+.
References
[1] Patent: US2006/4049, 2006, A1. Location in patent: Page/Page column 49
[2] Patent: WO2012/131379, 2012, A1. Location in patent: Page/Page column 25
[3] Patent: US2014/206703, 2014, A1. Location in patent: Paragraph 0106; 0107
(S)-3-PIPERIDINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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