ChemicalBook > CAS DataBase List > ETHYL 3-PIPERIDIN-4-YLPROPANOATE

ETHYL 3-PIPERIDIN-4-YLPROPANOATE

Product Name
ETHYL 3-PIPERIDIN-4-YLPROPANOATE
CAS No.
71879-55-5
Chemical Name
ETHYL 3-PIPERIDIN-4-YLPROPANOATE
Synonyms
Ethyl 4-piperidinepropanoate;ethyl 3-(4-piperidyl)propanoate;ETHYL 3-PIPERIDIN-4-YLPROPANOATE;4-(2-Ethoxycarbonylethyl)piperidine;4-piperidinepropanoic acid, ethyl ester;3-(4-piperidinyl)propanoic acid ethyl ester;3-Piperidin-4-yl-propionic acid ethyl ester
CBNumber
CB21517985
Molecular Formula
C10H19NO2
Formula Weight
185.26
MOL File
71879-55-5.mol
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ETHYL 3-PIPERIDIN-4-YLPROPANOATE Property

Boiling point:
252℃
Density 
0.959
Flash point:
106℃
pka
10.58±0.10(Predicted)
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Matrix Scientific
Product number
040676
Product name
Ethyl 3-piperidin-4-ylpropanoate
Packaging
500mg
Price
$315
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0392451
Product name
ETHYL-3-(PIPERIDIN-4-YL)PROPANOATE
Purity
95.00%
Packaging
5MG
Price
$499.25
Updated
2021/12/16
AK Scientific
Product number
1159AC
Product name
Ethyl3-(piperidin-4-yl)propanoate
Packaging
5g
Price
$1171
Updated
2021/12/16
Crysdot
Product number
CD11067630
Product name
Ethyl3-(piperidin-4-yl)propanoate
Purity
95+%
Packaging
1g
Price
$385
Updated
2021/12/16
Alichem
Product number
71879555
Product name
Ethyl3-(piperidin-4-yl)propanoate
Packaging
1g
Price
$400
Updated
2021/12/16
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ETHYL 3-PIPERIDIN-4-YLPROPANOATE Chemical Properties,Usage,Production

Synthesis

123293-78-7

71879-55-5

General procedure for the synthesis of ethyl 3-piperidine-4-propanoate from ethyl (E)-3-(pyridin-4-yl)acrylate: a mixture of ethyl (E)-3-(pyridin-4-yl)acrylate (3 g, 16.95 mmol) and a palladium/carbon catalyst (0.5 g) in methanol (30 mL) was stirred at 40°C under a hydrogen atmosphere of 276 kPa (40 Psi) The reaction was carried out overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated in vacuum to afford ethyl 3-piperidine-4-propionate (3 g, 95.8% yield). The product was analyzed by electrospray ionization mass spectrometry (ESI-MS), and the molecular ion peak (M+H)+ was measured to be 186, which was in accordance with the theoretically calculated molecular weight of 185.2 for C10H19NO2.

References

[1] Patent: WO2014/131855, 2014, A1. Location in patent: Page/Page column 68
[2] Journal of the Chemical Society, 1951, p. 1406,1408
[3] Journal of the Chemical Society, 1951, p. 1406,1408
[4] Chemical and Pharmaceutical Bulletin, 1993, vol. 41, # 3, p. 529 - 538
[5] Chemical and Pharmaceutical Bulletin, 1986, vol. 34, # 9, p. 3747 - 3761

ETHYL 3-PIPERIDIN-4-YLPROPANOATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 3-PIPERIDIN-4-YLPROPANOATE Suppliers

Wuhan Chemwish Technology Co., Ltd
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ShangHai KenEn Chemical Technology Co., Ltd.
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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Shanghai zhigan biotechnology co., LTD
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Zhejiang J&C Biological Technology Co.,Limited
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71879-55-5, ETHYL 3-PIPERIDIN-4-YLPROPANOATERelated Search:


  • 3-Piperidin-4-yl-propionic acid ethyl ester
  • 3-(4-piperidinyl)propanoic acid ethyl ester
  • ethyl 3-(4-piperidyl)propanoate
  • ETHYL 3-PIPERIDIN-4-YLPROPANOATE
  • 4-piperidinepropanoic acid, ethyl ester
  • 4-(2-Ethoxycarbonylethyl)piperidine
  • Ethyl 4-piperidinepropanoate
  • 71879-55-5