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3-AMINOETHYLTHIOPHENE HCL

Product Name
3-AMINOETHYLTHIOPHENE HCL
CAS No.
34843-84-0
Chemical Name
3-AMINOETHYLTHIOPHENE HCL
Synonyms
2-(Thiophen-3-yl);3-AMino-ethyl thiophene;3-AMINOETHYLTHIOPHENE HCL;3-Thiopheneethanamine hydrochloride;3-aminoethylthiophene hydrochloride;Thiophene-3-ethylaMine hydrochloride;2-(3-Thienyl)ethanamine hydrochloride;2-(3-thienyl)ethylaMine hydrochloride;2-(Thien-3-yl)ethylamine hydrochloride;3-(2-Aminoethyl)thiophene hydrochloride
CBNumber
CB21519611
Molecular Formula
C6H10ClNS
Formula Weight
163.67
MOL File
34843-84-0.mol
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3-AMINOETHYLTHIOPHENE HCL Property

Melting point:
215-216℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
Appearance
White to off-white Powder
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Safety

HazardClass 
IRRITANT
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B587735
Product name
2-(thiophen-3-yl)ethanaminehydrochloride
Packaging
5g
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
OR40114
Product name
3-(2-Aminoethyl)thiophenehydrochloride
Packaging
1g
Price
$73
Updated
2021/12/16
SynQuest Laboratories
Product number
7H30-5-X3
Product name
3-(2-Aminoethyl)thiophenehydrochloride
Packaging
1g
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54459
Product name
3-Aminoethylthiophene hydrochloride
Packaging
100mg
Price
$82
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA54459
Product name
3-Aminoethylthiophene hydrochloride
Packaging
250mg
Price
$102.5
Updated
2021/12/16
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3-AMINOETHYLTHIOPHENE HCL Chemical Properties,Usage,Production

Synthesis

13781-53-8

34843-84-0

The general procedure for the synthesis of 3-thiophene ethylamine hydrochloride from 3-thiopheneacetonitrile was as follows: thiophen-3-ylacetonitrile (2.0 g, 16.2 mmol) was dissolved in tetrahydrofuran (36 mL), and borane-dimethyl sulfide complex (3.0 mL, 30.4 mmol) was slowly added. The reaction mixture was heated to reflux for 16 hours. Upon completion of the reaction, methanol was added slowly at room temperature to terminate the reaction. Subsequently, saturated HCl/methanol solution (10 mL) was added and stirred at room temperature for 20 minutes. The reaction solution was concentrated to give the initial solid product. The solid was washed with ether (20 mL) to afford the target compound 3-thiophene ethylamine hydrochloride (Compound 41A) as a white solid (2.5 g, yield: 94%).

References

[1] Patent: CN108250128, 2018, A. Location in patent: Paragraph 0698; 0700; 0701; 0702
[2] Patent: WO2007/146759, 2007, A2. Location in patent: Page/Page column 24
[3] Patent: WO2007/146758, 2007, A2. Location in patent: Page/Page column 33
[4] Journal of Medicinal Chemistry, 2014, vol. 57, # 9, p. 3687 - 3706
[5] Patent: WO2012/114252, 2012, A1. Location in patent: Page/Page column 46

3-AMINOETHYLTHIOPHENE HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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34843-84-0, 3-AMINOETHYLTHIOPHENE HCLRelated Search:

5-bromo-3-(bromomethyl)benzo[b]thiophene 2-AMINO-3-(5-CHLOROBENZOóB!THIOPHEN-3-YL)PROPANOIC ACID, TECH 2-AMINO-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE METHYL 2-AMINO-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C] PYRIDINE-3-CARBOXYLATE Rocepafant 6-[5-CHLORO-1-(4-METHOXYPHENYL)-6-OXO-1,6-DIHYDRO-4-PYRIDAZINYL]-2-(1H-PYRROL-1-YL)-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE 2-AMINO-6-[5-CHLORO-1-(4-METHOXYPHENYL)-6-OXO-1,6-DIHYDRO-4-PYRIDAZINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE 6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-(([4-(DIMETHYLAMINO)PHENYL]METHYLENE)AMINO)-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBONITRILE AP 159 METHYL 2-[(([(4-CHLOROBENZYL)OXY]AMINO)METHYLENE)AMINO]-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE 7-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-[(2,4-DICHLOROBENZYL)SULFANYL]-3-METHYL-5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5]THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE METHYL 6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-([(DIMETHYLAMINO)METHYLENE]AMINO)-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE METHYL 2-([(4-CHLOROANILINO)CARBONYL]AMINO)-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE 7-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-METHYL-2-SULFANYL-5,6,7,8-TETRAHYDROPYRIDO[4',3':4,5]THIENO[2,3-D]PYRIMIDIN-4(3H)-ONE METHYL 6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-2-[(METHYLSULFONYL)AMINO]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE METHYL 2-[(2-CHLOROBENZOYL)AMINO]-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE METHYL 2-[BIS(METHYLSULFONYL)AMINO]-6-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE-3-CARBOXYLATE BUTTPARK 60\40-91

  • 3-AMINOETHYLTHIOPHENE HCL
  • 3-aminoethylthiophene hydrochloride
  • 2-Thiophen-3-yl-ethylamine hydrochloride
  • 2-(3-Thienyl)ethanamine hydrochloride
  • 2-(Thien-3-yl)ethylamine hydrochloride
  • 3-Thiopheneethanamine hydrochloride
  • 3-(2-Aminoethyl)thiophene hydrochloride
  • 2-(thiophen-3-yl)ethan-1-aMine hydrochloride
  • 2-(3-thienyl)ethylaMine hydrochloride
  • 2-(Thiophen-3-yl)
  • Thiophene-3-ethylaMine hydrochloride
  • 3-AMino-ethyl thiophene
  • 3-AMINOETHYLTHIOPHENE HCL ISO 9001：2015 REACH
  • 2-(thiophen-3-yl)ethanamine hydrochloride (1:1)
  • 34843-84-0