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ethyl 2-(3,5-dimethoxyphenyl)acetate

Product Name
ethyl 2-(3,5-dimethoxyphenyl)acetate
CAS No.
65976-77-4
Chemical Name
ethyl 2-(3,5-dimethoxyphenyl)acetate
Synonyms
Ethyl 2-(3,5-dimethoxyphenyl);ethyl 2-(3,5-dimethoxyphenyl)acetate;(3,5-dimethoxy-phenyl)-acetic acid ethyl ester;Benzeneacetic acid, 3,5-diMethoxy-, ethyl ester
CBNumber
CB21560608
Molecular Formula
C12H16O4
Formula Weight
224.25
MOL File
65976-77-4.mol
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ethyl 2-(3,5-dimethoxyphenyl)acetate Property

Boiling point:
144-146 °C(Press: 5 Torr)
Density 
1.084±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
Appearance
Colorless to light yellow Liquid
InChI
InChI=1S/C12H16O4/c1-4-16-12(13)7-9-5-10(14-2)8-11(6-9)15-3/h5-6,8H,4,7H2,1-3H3
InChIKey
LPMABDMACJOZAT-UHFFFAOYSA-N
SMILES
C1(CC(OCC)=O)=CC(OC)=CC(OC)=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B124695
Product name
Ethyl2-(3,5-Dimethoxyphenyl)acetate
Packaging
500mg
Price
$130
Updated
2021/12/16
Matrix Scientific
Product number
128158
Product name
Ethyl3,5-dimethoxyphenylacetate
Purity
97%
Packaging
1g
Price
$298
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0392245
Product name
ETHYL-2-(3,5-DIMETHOXYPHENYL)ACETATE
Purity
95.00%
Packaging
5MG
Price
$504.02
Updated
2021/12/16
AK Scientific
Product number
0127AC
Product name
Ethyl2-(3,5-dimethoxyphenyl)acetate
Packaging
25g
Price
$610
Updated
2021/12/16
Crysdot
Product number
CD12045689
Product name
Ethyl2-(3,5-dimethoxyphenyl)acetate
Purity
98%
Packaging
25g
Price
$411
Updated
2021/12/16
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ethyl 2-(3,5-dimethoxyphenyl)acetate Chemical Properties,Usage,Production

Synthesis

64-17-5

4670-10-4

65976-77-4

Step 1: 3,5-dimethoxyphenylacetic acid (1.35 g, 6.88 mmol) was dissolved in ethanol and concentrated hydrochloric acid (4 drops) was added. The reaction mixture was heated to reflux at 85°C for 16 hours. After completion of the reaction, it was cooled to room temperature and concentrated under reduced pressure. The residue was diluted with distilled water (20 mL) and extracted with dichloromethane (25 mL x 3). The organic layers were combined, washed with saturated saline (50 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure to give ethyl 2-(3,5-dimethoxyphenyl)acetate (2.85 g, 100%) as a yellow solid.

References

[1] Patent: WO2014/144737, 2014, A1. Location in patent: Paragraph 00718
[2] Journal of Medicinal Chemistry, 1984, vol. 27, # 2, p. 190 - 195
[3] MedChemComm, 2013, vol. 4, # 2, p. 332 - 339
[4] Chinese Journal of Chemistry, 2010, vol. 28, # 6, p. 1041 - 1043

ethyl 2-(3,5-dimethoxyphenyl)acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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ethyl 2-(3,5-dimethoxyphenyl)acetate Suppliers

Shanghai yuanzuo medical technology co., LTD
Tel
021-31775309; 15221510662
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China
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Accela ChemBio Co.,Ltd.
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021-50795510 4000665055
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021-50795055
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sales@accelachem.com
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China
ProdList
11035
Advantage
64
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
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info@sagechem.com
Country
China
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Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
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Country
China
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Changzhou Boren Chemical Technology Co., Ltd.
Tel
0519-82085178 13861172460
Fax
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Country
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ProdList
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Changzhou Tianrui Pharmaceutical Technology Co., Ltd.
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Quzhou AMK BioTech Co., Ltd
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
Country
China
ProdList
131957
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58
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View Lastest Price from ethyl 2-(3,5-dimethoxyphenyl)acetate manufacturers

Shanghai Rlavie Technology Co ltd
Product
Ethyl 2-(3,5-dimethoxyphenyl)acetate 65976-77-4
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%min
Supply Ability
100kgs/month
Release date
2021-11-21

65976-77-4, ethyl 2-(3,5-dimethoxyphenyl)acetateRelated Search:


  • (3,5-dimethoxy-phenyl)-acetic acid ethyl ester
  • Ethyl 2-(3,5-dimethoxyphenyl)
  • ethyl 2-(3,5-dimethoxyphenyl)acetate
  • Benzeneacetic acid, 3,5-diMethoxy-, ethyl ester
  • 65976-77-4