1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE

ChemicalBook > CAS DataBase List > 1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE

1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE

Product Name: 1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE
CAS No.: 54125-02-9
Chemical Name: 1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE
Synonyms: DK814;DANISHEFSKY'S DIENE;Danishefsky-Kitahara diene.;1-METHOXY-3-(TRIMETHYLSILOXY)BUTADIENE;TRANS-1-METHOXY-3-TRIMETHYLSILOXY- &;1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE;1-METHOXY-3-TRIMETHYLSILYLOXY-1,3-BUTADIENE;1-Methoxy-3-trimethylsiloxy-1,3-butadiene ,95%;1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE, 98+%;TRANS-1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE
CBNumber: CB2162111
Molecular Formula: C8H16O2Si
Formula Weight: 172.3
MOL File: 54125-02-9.mol

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1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE Property

Boiling point:: 68-69 °C/14 mmHg (lit.)
Density: 0.885 g/mL at 25 °C (lit.)
refractive index: n20/D 1.454(lit.)
Flash point:: 113 °F
storage temp.: 2-8°C
Specific Gravity: 0.89
Water Solubility: Miscible with most organic solvents. Immiscible with water.
Hydrolytic Sensitivity: 8: reacts rapidly with moisture, water, protic solvents
Sensitive: Moisture Sensitive
Merck: 14,6001
BRN: 1616761
CAS DataBase Reference: 54125-02-9(CAS DataBase Reference)

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Safety

Risk Statements: 10
Safety Statements: 23-24/25
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
F: 10-21
TSCA: No
HazardClass: 3
PackingGroup: III
HS Code: 2931900090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 212830
Product name: trans-1-Methoxy-3-trimethylsiloxy-1,3-butadiene
Purity: 95%
Packaging: 1g
Price: $59.9
Updated: 2024/03/01

Sigma-Aldrich

Product number: 212830
Product name: trans-1-Methoxy-3-trimethylsiloxy-1,3-butadiene
Purity: 95%
Packaging: 5g
Price: $190
Updated: 2024/03/01

Alfa Aesar

Product number: L06100
Product name: 1-Methoxy-3-trimethylsiloxy-1,3-butadiene, 94%
Packaging: 1g
Price: $46.65
Updated: 2024/03/01

Alfa Aesar

Product number: L06100
Product name: 1-Methoxy-3-trimethylsiloxy-1,3-butadiene, 94%
Packaging: 5g
Price: $174
Updated: 2024/03/01

Alfa Aesar

Product number: L14672
Product name: 1-Methoxy-3-trimethylsiloxy-1,3-butadiene, 96%
Packaging: 1g
Price: $66.65
Updated: 2024/03/01

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1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE Chemical Properties,Usage,Production

Uses

1-Methoxy-3-trimethylsiloxy-1,3-butadiene is employed as a reagent in Mannich-Michael reaction for the synthesis of piperidinones and enaminones. As Diels-Alder diene, it is used in the synthesis of pyridones and pyranones, sulfone analogues of griseofulvin (sulfogriseofulvins) and 4H-1-aminopyrroles and 4, 5H-pyrazoles.

General Description

trans-1-methoxy-3-trimethylsiloxy-1,3-butadiene is a funtionalized Diels-Alder diene. Mukaiyama-Michael-type addition/heterocyclization of trans-1-methoxy-3-trimethylsiloxy-1,3-butadiene (Danishefsky′s diene) with 1,2-diaza-1,3-butadiene has been investigated. Asymmetric hetero-Diels-Alder cyclization of Danishefsky′s diene with benzaldehyde catalyzed by mesoporous inorganic/metalorganic hybrid materials has been reported.

Purification Methods

It may contain up to 1% of the precursor 4-methoxybut-4-ene-2-one. It is easily purified by distilling through a Vigreux column (p 11) in a vacuum and taking the middle fraction. [Danishefsky & Kitihara J Am Chem Soc 96 7807 1974, Danishefsky Acc Chem Res 14 400 1981.]

1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE Preparation Products And Raw materials

Raw materials

Sodium acetate Acetonitrile Acetylacetaldehyde dimethyl acetal Lithium bromide Chlorotrimethylsilane Sodium Zinc chloride Triethylamine Sodium iodide Diethyl ether Benzene

Preparation Products

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1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE Suppliers

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54125-02-9, 1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENERelated Search:

Triethoxysilane Octamethylcyclotetrasiloxane Vinyltrimethoxysilane ALLYLOXYTRIMETHYLSILANE Ethoxytrimethylsilane 4-Methoxy-2-(trimethylsiloxy)-1,3-butadiene,1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE,TRANS-1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE 2-(Trimethylsiloxy)-1,3-butadiene METHOXYTRIMETHYLSILANE DIMETHYLETHOXYSILANE VINYLOXYTRIMETHYLSILANE 1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE ISOPROPENYLOXYTRIMETHYLSILANE 1-METHOXY-1,3-BUTADIENE (1E 3Z)-1-METHOXY-2-METHYL-3-(TRIMETHYL& DIMETHYLMETHOXYSILANE Silane, methoxy- TRANS-3-(TERT-BUTYLDIMETHYLSILYLOXY)-1-METHOXY-1,3-BUTADIENE (1Z)-1-(Benzyloxy)-3-methoxy-1-(trimethylsiloxy)-1,3-butadiene

TRANS-1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE

TRANS-1-METHOXY-3-(TRIMETHYLSILYLOXY)-1,3-BUTADIENE

DANISHEFSKY'S DIENE

1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE

1-METHOXY-3-(TRIMETHYLSILOXY)BUTADIENE

1-METHOXY-3-TRIMETHYLSILYLOXY-1,3-BUTADIENE

TRANS-1-METHOXY-3-TRIMETHYLSILOXY- &

1-Methoxy-3-(trimethylsiloxy)butadiene(Danishefsky`sDiene)

Silane, (2E)-3-methoxy-1-methylene-2-propenyloxytrimethyl-

Danishefsky-Kitahara diene.

1-METHOXY-3-TRIMETHYLSILOXY-1,3-BUTADIENE, 98+%

1-Methoxy-3-trimethylsiloxy-1,3-butadiene ,95%

(1E)-3-(Trimethylsilyloxy)-1-methoxy-1,3-butadiene

(E)-1-Methoxy-3-(trimethylsiloxy)-1,3-butadiene

(E)-1-Methoxy-3-[(trimethylsilyl)oxy]-1,3-butadiene

[[(E)-3-Methoxy-1-methylene-2-propenyl]oxy]trimethylsilane

Methyl[(1E)-3-(trimethylsiloxy)-1,3-butadienyl] ether

(E)-(4-methoxybuta-1,3-dien-2-yloxy)trimethylsilane

[(E)-3-Methoxy-1-methylene-allyloxy]-trimethyl-silane

trans-1-Methoxy-3-trimethylsilyloxy-1,3-butadiene for synthesis

trans-1-Methoxy-3-trimethylsiloxy-1,3-butadiene,Danishefsky’s diene

Silane, [[(2E)-3-Methoxy-1-Methylene-2-propen-1-yl]oxy]triMethyl-

[(4-Methoxybuta-1,3-dien-2-yl)oxy]triMethylsilane

trans-1-Methoxy-3-triMethylsiloxy-1,3-butadiene 95%

(2E)-3-Methoxy-1-methylene-2-propen-1-yl]oxy]trimethylsilane

DK814

54125-02-9

C8H16O2Si1

CH33SiOCCH2CHCHOCH3

Building Blocks

Enol Ethers

Organic Building Blocks

Oxygen Compounds

Si-O Compounds

Silicon Compounds (for Synthesis)

Monoalkoxysilanes

Si (Classes of Silicon Compounds)

Vinylsilanes, Allylsilanes