2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE
- Product Name
- 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE
- CAS No.
- 408502-23-8
- Chemical Name
- 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE
- Synonyms
- 2-methoxypyridine-4-borate acid;2-methoxypyridine-4-boronic acid pinacolate;2-Methoxy-4-pyridylboronic Acid Pinacol Ester;2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE;2-Methoxylypyrinine-4-boronic acid pinacolate;2-METHOXYPYRIDINE-4-BORONIC ACID PINACOL ESTER;2-Methoxypyridine-4-boronic acid, pinacol ester 97%;2-Methoxy-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-(2-Methoxy-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane;2-Methoxy-4-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyridine
- CBNumber
- CB2169918
- Molecular Formula
- C12H18BNO3
- Formula Weight
- 235.09
- MOL File
- 408502-23-8.mol
2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE Property
- Melting point:
- 36 °C
- Boiling point:
- 329.1±27.0 °C(Predicted)
- Density
- 1.06±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- soluble in Methanol
- form
- powder to lump
- pka
- 2.56±0.10(Predicted)
- color
- White to Almost white
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M3186
- Product name
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Packaging
- 1G
- Price
- $192
- Updated
- 2025/07/31
- Product number
- CS-W005511
- Product name
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Purity
- ≥97.0%
- Packaging
- 1g
- Price
- $74
- Updated
- 2021/12/16
- Product number
- M23570
- Product name
- 2-Methoxy-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $110
- Updated
- 2021/12/16
- Product number
- CS-W005511
- Product name
- 2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- Purity
- ≥97.0%
- Packaging
- 5g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- BOR0004638
- Product name
- 2-METHOXYLYPYRININE-4-BORONIC ACID PINACOLATE
- Purity
- 95.00%
- Packaging
- 0.25G
- Price
- $748
- Updated
- 2021/12/16
2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE Chemical Properties,Usage,Production
Synthesis
98197-72-9
73183-34-3
408502-23-8
A mixture of 4-iodo-2-methoxypyridine (0.099 g, 0.42 mmol), pinacol ester of bis(boronic acid) (0.12 g, 0.47 mmol), and potassium acetate (0.13 g, 1.31 mmol) was added to a microwave reactor containing dimethylformamide (1 mL) protected by nitrogen and nitrogen was bubbled for 5 min. Subsequently, [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride complex with dichloromethane (1:1) (0.017 g, 0.02 mmol) was added, and the reactor was sealed, and microwave irradiation was carried out for 4 hr at 80 °C. After completion of the reaction, the mixture was diluted with ethyl acetate and filtered through diatomaceous earth. The filtrate was washed sequentially with saturated aqueous sodium bicarbonate, water and brine, dried over anhydrous magnesium sulfate and concentrated to give 2-methoxypyridine-4-boronic acid pinacol ester (0.28 g, 82% yield) as a brown oil, which can be used directly in the next step of the reaction.LRMS (m/z): 236 (M + 1).
References
[1] Patent: WO2011/76419, 2011, A1. Location in patent: Page/Page column 131
[2] Patent: EP2338888, 2011, A1. Location in patent: Paragraph 0213; 0214
2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE manufacturers
- Product
- 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE 408502-23-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-27
- Product
- 2-METHOXYLYPYRIDINE-4-BORONIC ACID PINACOLATE 408502-23-8
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09