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Diltiazem EP Impurity B

Product Name
Diltiazem EP Impurity B
CAS No.
87447-47-0
Chemical Name
Diltiazem EP Impurity B
Synonyms
DiltiazeM IMpurity B;Diltiazem EP Impurity B;Diltiazem Acetoxy Lactum;Acetoxy Lactam Diltiazem;Diltiazem Hydrochloride Impurity B;(2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2;Diltiazem Hydrochloride EP Impurity B;Des[5-(2-dimethylamino)ethyl] Diltiazem;(2S-cis)-3-(acetyloxy)-2,3-dihydro-2-*(4-methoxyp;(2S-CIS)-3-(ACETYLOXY)-2,3-DIHYDRO-2-(4- METHOXYPHE
CBNumber
CB2178116
Molecular Formula
C18H17NO4S
Formula Weight
343.4
MOL File
87447-47-0.mol
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Diltiazem EP Impurity B Property

Melting point:
147-150?C
Boiling point:
535.9±50.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
12.99±0.60(Predicted)
color 
White to Off-White
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A9559
Product name
(2S)-cis-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
Purity
analytical standard
Packaging
5g
Price
$44
Updated
2022/05/15
TRC
Product number
D288950
Product name
Des[5-(2-dimethylamino)ethyl]Diltiazem
Packaging
250mg
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21108
Product name
Des[5-(2-dimethylamino)ethyl] diltiazem
Packaging
25mg
Price
$200.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CCH0007142
Product name
(2S-CIS)-3-(ACETYLOXY)2,3-DIHYDRO-2-(4-METHOXY-PHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE
Purity
95.00%
Packaging
25MG
Price
$269.85
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD21108
Product name
Des[5-(2-dimethylamino)ethyl] diltiazem
Packaging
50mg
Price
$364
Updated
2021/12/16
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Diltiazem EP Impurity B Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Diltiazem (D460620) intermediate (impurity B).

Diltiazem EP Impurity B Preparation Products And Raw materials

Raw materials

Preparation Products

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Diltiazem EP Impurity B Suppliers

Canada 1 China 45 India 7 Switzerland 1 United Kingdom 1 United States 6 Global 61
Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71

87447-47-0, Diltiazem EP Impurity BRelated Search:

Diltiazem N-Oxide Diltiazem impurity diltiazem hydrochloride Deacetyl-O-demethyl Diltiazem Hydrochloride O-Desacetyl-N-desmethyl Diltiazem Diltiazem Impurity 3 (2S,3S)-3-(Acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 1-oxide DESACETYL DILTIAZEM HCL (2S-cis)-(+)-2,3-Dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Diltiazem EP Impurity C Diltiazem hydrochloride N,N-Didesmethyl Diltiazem Hydrochloride (2R-cis)-3-acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one monohydrochloride 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, (2S-trans)- O-Desmethyl Diltiazem Hydrochloride DESACETYL DILTIAZEM HYDROCHLORIDE (50 MG) N-DESMETHYLDILTIAZEM, HYDROCHLORIDE Diltiazem EP Impurity B

  • (2S-CIS)-3-(ACETYLOXY)-2,3-DIHYDRO-2-(4-METHOXY-PHENYL)-1,5-BENZOTHIAZEPIN-4(5H)-ONE
  • (2S-cis)-3-(acetyloxy)-2,3-dihydro-2-*(4-methoxyp
  • (2S-CIS)-3-(ACETYLOXY)-2,3-DIHYDRO-2-(4- METHOXYPHE
  • Diltiazem Acetoxy Lactum
  • (2S-cis)-3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)....
  • Des[5-(2-dimethylamino)ethyl] Diltiazem
  • (2S,3S)-3-(Acetyloxy)-2,3-dihydro-2-(4-Methoxyphenyl)-1,5-benzothiazepin-4(5H)-one
  • DiltiazeM IMpurity B
  • (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2
  • (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate
  • 1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-, (2S,3S)-
  • Acetoxy Lactam Diltiazem
  • (2S)-cis-3-(Acetyloxy)-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one analytical standard
  • Diltiazem Hydrochloride EP Impurity B
  • (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepin-3-yl acetate (Diltiazem Impurity)
  • Diltiazem Hydrochloride Impurity B
  • Diltiazem EP Impurity B
  • Diltiazem EP Impurity B (2S,3S)-2-(4-Methoxyphenyl)-4-oxo-2,3,4,5-tetrahydro- 1,5-benzothiazepin-3-yl acetate
  • 87447-47-0
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