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CACODYLIC ACID

Product Name
CACODYLIC ACID
CAS No.
75-60-5
Chemical Name
CACODYLIC ACID
Synonyms
Ansar;Arsan;Dilic;Erase;Salvo;Phytar;moncide;ANSAR(R);alkargen;ansar138
CBNumber
CB2194114
Molecular Formula
C2H7AsO2
Formula Weight
138
MOL File
75-60-5.mol
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CACODYLIC ACID Property

Melting point:
195-198 °C
Boiling point:
>200 °C
storage temp. 
Store at RT.
solubility 
Methanol (Slightly), Water (Slightly)
form 
Powder/Solid
pka
1.57(at 25℃)
color 
White
Water Solubility 
Soluble in water (50 mg/ml), water (2000 at 25°C), alcohols, and acetic acid. Insoluble in ether.
Sensitive 
Hygroscopic
Merck 
14,1604
BRN 
1736965
Stability:
Aqueous solutions react violently with active metals. Incompatible with strong oxidizing agents, strong bases.
CAS DataBase Reference
75-60-5(CAS DataBase Reference)
IARC
2B (Vol. 100C) 2012
EPA Substance Registry System
Cacodylic acid (75-60-5)
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Safety

Hazard Codes 
T,N
Risk Statements 
23/25-50/53
Safety Statements 
20/21-28-45-60-61
RIDADR 
UN 1572 6.1/PG 2
WGK Germany 
3
RTECS 
CH7525000
3-10
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29310099
Hazardous Substances Data
75-60-5(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 1350 mg/kg (Bailey, White)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H350May cause cancer

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
20835
Product name
Cacodylic acid
Purity
≥99.0%
Packaging
10g
Price
$99.2
Updated
2024/03/01
Sigma-Aldrich
Product number
20835
Product name
Cacodylic acid
Purity
≥99.0%
Packaging
50g
Price
$213
Updated
2024/03/01
Sigma-Aldrich
Product number
20835
Product name
Cacodylic acid
Purity
≥99.0%
Packaging
50g-f
Price
$212
Updated
2021/12/16
Sigma-Aldrich
Product number
20835
Product name
Cacodylic acid
Purity
≥99.0%
Packaging
10g-f
Price
$79.8
Updated
2021/12/16
TCI Chemical
Product number
C1072
Product name
Cacodylic Acid
Packaging
5G
Price
$30
Updated
2021/12/16
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CACODYLIC ACID Chemical Properties,Usage,Production

Description

Cacodylic acid is a colorless, odorless,crystalline solid arsenic compound. Molecular weight =138.02; Boiling point=200℃; Freezing/Melting point 5192℃. Hazard Identification (based on NFPA-704 MRating System): Health 4, Flammability 0, Reactivity 0.[NJ]Highly soluble in water.

Chemical Properties

white crystals or powder

Uses

antieczema, dermatologic, herbicide

Uses

A useful arsenic acid for proteomics research. It a good substitute for phosphate in applications to avoid phosphates. Cacodylic Acid is useful for some DNA applications and is also popular in microscopy.

Uses

Cacodylic acid is used for dermatologic treatment in cronic eczema, anemia and as a tonic.

Definition

ChEBI: The organoarsenic compound that is arsenic acid substituted on the central arsenic atom with two methyl groups.

General Description

A colorless, odorless crystalline solid. Melting point 195-196°C. Toxic by ingestion and irritating to skin and eyes.

Air & Water Reactions

Hygroscopic. Water soluble.

Reactivity Profile

CACODYLIC ACID is a weak acid. Dissolves in water to yield solutions containing more hydrogen ions than pure water contains and so having a pH less than 7.0. Is neutralized exothermically by all bases to produce water plus a salt. Reacts (but usually slowly) with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for the solid acid but are quite slow if the solid acid remains dry. The solid may absorb enough water from the air and dissolve sufficiently in CACODYLIC ACID to corrode or dissolve iron, steel, and aluminum parts and containers. Reacts with cyanide salts to generate gaseous hydrogen cyanide. Flammable and/or toxic gases and heat may be generated with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Also may react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still some heat. Can be oxidized exothermically by strong oxidizing agents and reduced by strong reducing agents; a wide variety of products is possible. May initiate polymerization reactions; may catalyze (increase the rate of) chemical reactions.

Hazard

Toxic by ingestion.

Health Hazard

Chemical is essentially non-irritating in contact with skin or eyes. Ingestion causes arsenic poisoning, but symptoms are delayed.

Fire Hazard

Behavior in Fire: May form toxic oxides of arsenic when heated.

Potential Exposure

Used as an herbicide, soil sterilant and intimber thinning. Has been used as a chemical warfare agent.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seekmedical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, getmedical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Note to physician: For severe poisoning BAL [British AntiLewisite, dimercaprol, dithiopropanol (C3H8OS2)] has beenused to treat toxic symptoms of certain heavy metals poisoning including arsenic. Although BAL is reported to have alarge margin of safety, caution must be exercised, becausetoxic effects may be caused by excessive dosage. Most can beprevented by premedication with 1-ephedrine sulfate (CAS:134-72-5). For milder poisoning penicillamine (not penicillin)has been used, both with mixed success. Side effects occurwith such treatment and it is never a substitute for controllingexposure. It can only be done under strict medical care.

storage

Color Code—Blue: Health Hazard/Poison: Storein a secure poison location. Prior to working with cacodylicacid you should be trained on its proper handling andstorage. A regulated, marked area should be establishedwhere this chemical is handled, used, or stored in compliance with OSHA Standard 1910.1045. Store in tightlyclosed containers in a cool, well-ventilated area away fromoxidizing agents, chemically active metals, strong bases,moisture, fertilizers, seeds, insecticides, and fungicides.

Shipping

UN1572 Cacodylic acid & UN1688 Sodium Cacodylate, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN3465 Organoarsenic compound, solid, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required

Purification Methods

Recrystallise it from warm EtOH (3mL/g) by cooling and filtering. Dry it in a vacuum desiccator over CaCl2. It has also been recrystallised twice from propan-2-ol. [Koller & Hawkridge J Am Chem Soc 107 7412 1985, Beilstein 4 IV 3681.]

Incompatibilities

A strong reducing agent. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Aqueous solution reacts violently with chemically active metals releasing toxic arsenic fumes. Incompatible with oxidizers, sulfuric acid; caustics (strong bases), reducing agents; ammonia, amines, isocyanates, alkylene oxides; epichlorohydrin.

CACODYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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75-60-5, CACODYLIC ACIDRelated Search:


  • Cacodylic acid >=99.0%
  • ANSAR(R)
  • CACODYLIC ACID
  • Cacodylie acid
  • HYDROXYDIMETHYLARSINE OXIDE
  • DIMETHYLHYDROXYARSINE OXIDE
  • DIMETHYLARSINIC ACID
  • DIMETHYLARSONIC ACID
  • SILVISAR(R)
  • PHYTAR(R)
  • RAD-E-CATE 35(R)
  • Acide cacodylique
  • Acide dimethylarsinique
  • acidecacodylique
  • acidecacodylique(french)
  • acidedimethylarsenique(french)
  • acidedimethylarsinique
  • Agent blue
  • agentblue
  • alkargen
  • Ansar
  • Ansar 138
  • ansar138
  • Arsan
  • Arsine oxide, dimethylhydroxy-
  • Arsine oxide, hydroxydimethyl-
  • arsinicacid,dimethyl-
  • Bolls-Eye
  • cacodylic
  • Chexmate
  • cottonaidehc
  • Dilic
  • Dimethylarsenic acid
  • dimethylarsenicacid
  • dimethyl-arsinicaci
  • dimethylhydroxy-arsineoxid
  • Erase
  • hydroxydimethyl-arsineoxid
  • Kyselina kakodylova
  • kyselinakakodylova
  • moncide
  • Phytar
  • Phytar 138
  • Phytar 560
  • phytar138
  • phytar600
  • Rad-e-cate 25
  • Rad-e-cate 35
  • DIMETHYLARSINIC ACID (CACODYLIC ACID)
  • C95-DOLICHYL-MPDA
  • Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide
  • Cacodylic acid, Dimethylarsinic acid, Dimethylarsonic acid, Hydroxydimethylarsine oxide
  • Cacodylic Acid, OMniPur(R)
  • As,As-DiMethylarsinic Acid
  • NSC 103115
  • NSC 71157
  • NSC 71158
  • Dimethylhydroxyarsine Oxide Hydroxydimethylarsine Oxide