ChemicalBook > CAS DataBase List > 1-BENZYLPYRROLIDIN-3-YL-METHANOL

1-BENZYLPYRROLIDIN-3-YL-METHANOL

Product Name: 1-BENZYLPYRROLIDIN-3-YL-METHANOL
CAS No.: 5731-17-9
Chemical Name: 1-BENZYLPYRROLIDIN-3-YL-METHANOL
Synonyms: CHEMBRDG-BB 4003810;1-BENZYL-DL-BETA-PROLINOL;1-Benzylpyrrolidine-3-methanol;1-Benzyl-3-pyrrolidinemethanol;1-BENZYL-3-PYRROLIDIN-3-YLMETHANOL;1-BENZYL-3-HYDROXYMETHYLPYRROLIDINE;1-Benzyl-1H-pyrrolidin-3-yl-Methanol;(1-Benzyl-1H-pyrrolidin-3-yl)Methanol;3-HYDROXYMETHYL-N-BENZYL- PYRROLIDINE;1-(Phenylmethyl)-3-pyrrolidinemethanol
CBNumber: CB2194664
Molecular Formula: C12H17NO
Formula Weight: 191.27
MOL File: 5731-17-9.mol

Less

1-BENZYLPYRROLIDIN-3-YL-METHANOL Property

Boiling point:: 129 °C(Press: 0.9 Torr)
Density: 1.082±0.06 g/cm3(Predicted)
storage temp.: Store at room temperature
form: solid
pka: 14.93±0.10(Predicted)
Appearance: Light yellow to yellow Viscous liquid
InChI: InChI=1S/C12H17NO/c14-10-12-6-7-13(9-12)8-11-4-2-1-3-5-11/h1-5,12,14H,6-10H2
InChIKey: QPQQBJDSKDWQMJ-UHFFFAOYSA-N
SMILES: N1(CC2=CC=CC=C2)CCC(CO)C1
CAS DataBase Reference: 5731-17-9(CAS DataBase Reference)

Less

Safety

Hazard Codes: Xi,T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933998090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: ADE000012
Product name: 1-Benzylpyrrolidin-3-yl-methanol
Purity: Aldrich
Packaging: 1g
Price: $179
Updated: 2025/07/31

TRC

Product number: B289065
Product name: (1-Benzylpyrrolidin-3-yl)methanol
Packaging: 100mg
Price: $75
Updated: 2021/12/16

Matrix Scientific

Product number: 018164
Product name: 1-Benzylpyrrolidin-3-yl-methanol
Packaging: 1g
Price: $37
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50914
Product name: 1-Benzylpyrrolidin-3-yl-methanol
Packaging: 250mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50914
Product name: 1-Benzylpyrrolidin-3-yl-methanol
Packaging: 500mg
Price: $100
Updated: 2021/12/16

Less

1-BENZYLPYRROLIDIN-3-YL-METHANOL Chemical Properties,Usage,Production

Synthesis

51535-00-3

5731-17-9

Example A: Synthesis of N-benzyl-3-hydroxymethylpyrrolidine Step a: Reduction of methyl 1-benzyl-5-oxopyrrolidine-3-carboxylate to 1-benzyl-3-hydroxymethylpyrrolidine Under an inert atmosphere, methyl 1-benzyl-5-oxopyrrolidine-3-carboxylate (1.0 equiv, commercially available) was dissolved in toluene and the mixture was cooled to 0 °C. To the cooled mixture was slowly added a dimethyl sulfide solution of borane-dimethyl sulfide complex (3.75 equiv.). The reaction mixture was heated to 100°C-110°C and refluxed for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature, further cooled to -5 °C to -10 °C, and then sodium bicarbonate solution was added dropwise. The mixture was slowly warmed to room temperature and then refluxed for 2 hours. After the reaction mixture was cooled, the organic layer was separated and the aqueous layer was extracted with toluene. The combined toluene layers were washed sequentially with water and brine. Finally, the organic solvent was removed by evaporation under reduced pressure to afford the target product N-benzyl-3-hydroxymethylpyrrolidine in 99.14% yield.

References

[1] Patent: WO2006/18708, 2006, A2. Location in patent: Page/Page column 21-22
[2] Letters in Organic Chemistry, 2011, vol. 8, # 3, p. 155 - 162
[3] Patent: US2004/147502, 2004, A1. Location in patent: Page/Page column 36-37
[4] Organic Letters, 1999, vol. 1, # 5, p. 799 - 801
[5] Patent: US2005/165005, 2005, A1. Location in patent: Page/Page column 59-60

1-BENZYLPYRROLIDIN-3-YL-METHANOL Preparation Products And Raw materials

Raw materials

Preparation Products

Less

1-BENZYLPYRROLIDIN-3-YL-METHANOL Suppliers

Canada 1 China 109 Germany 2 India 2 United Kingdom 2 United States 20 Global 136

Anhui Dexinjia Biopharm Co., Ltd

Tel: 0531-82375892 15553111391
Email: 3276840968@qq.com
Country: China
ProdList: 301
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.

Tel: 21-54820552 18964669552
Fax: 086-21-64964478
Email: 188738128@qq.com
Country: China
ProdList: 310
Advantage: 66

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16075
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.

Tel: 010-81520996 13439320863
Fax: 010-81520996
Email: hengpugao@126.com
Country: China
ProdList: 159
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

skychemical Co.Ltd

Tel: 021-20958197 20965099
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 1183
Advantage: 57

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Shanghai Sheepchem Co., Ltd.

Tel: +86 (21) 6715-7650
Fax: +86 (21) 6715-7651
Email: sheepchem@163.com
Country: China
ProdList: 994
Advantage: 60

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Shanghai Hong-chuang Pharma Tech Co., Ltd.

Tel: 18151128828
Fax: -
Email: hc-sales@foxmail.com
Country: China
ProdList: 2647
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Shanghai Hobor Chemical Co., Ltd

Tel: 021-57790084; 13918007836
Fax: 021-51685238
Email: sales@hoborchem.com
Country: China
ProdList: 392
Advantage: 60

Chengdu Firster Pharmaceutical Co., Ltd.

Tel: 028-87078428 028-87074958
Fax: 8772-8116
Email: chengzhenyong@cdfirster.com
Country: China
ProdList: 2598
Advantage: 60

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Chengdu jingzhihuacheng Chemical Technology Co., Ltd.

Tel: 028-028-37664989 15900794981
Email: jingzhichem@163.com
Country: China
ProdList: 537
Advantage: 55

skychemical Co.Ltd

Tel: 021-20960837,QQ1332204249
Fax: 021-20960837
Email: sales@skychemical.com
Country: China
ProdList: 3341
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Changyan Chem & Tech Co., Ltd.

Tel: 021-20242659 18930833303
Fax: +86 (21) 2024-2659
Email: Sales@changyanchem.cn
Country: China
ProdList: 5001
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

parabiochem

Tel: 025-83453382-8005
Fax: 025-83453382
Email: sale@parabiochem.com
Country: China
ProdList: 9595
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Cck Pharmchem Co.,Ltd

Tel: 0512-68131995 13862051930
Fax: 0512-68131995
Country: China
ProdList: 360
Advantage: 55

Shanghai Kangman Biological Technology Co., Ltd.

Tel: 18800375331
Fax: 021-50908862
Email: kangmansales@163.com
Country: China
ProdList: 7570
Advantage: 55

Aikon International Limited

Tel: 025-58851090 15955137747
Fax: (6)02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15949
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai Wenjia Biomedical Technology Co., Ltd.

Tel: 15001899038 15001899038;
Email: wenjiayiyao@126.com
Country: China
ProdList: 996
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: alfa10@alfachem.cn
Country: China
ProdList: 12921
Advantage: 58

Nanjing Hengbei Chemicals Co., Ltd.

Tel: +86-25-58393656
Fax: +86-25-58393656
Email: sales@hengbeichem.cn
Country: China
ProdList: 6854
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Hebei Beckman Biotechnology Co., Ltd.

Tel: 15961617865 15961617865;
Email: 2245485247@qq.com
Country: China
ProdList: 4599
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: sales@accelachem.com
Country: China
ProdList: 10467
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-87569266 +86-17392581500
Fax: 029-88380327
Email: 1015@dideu.com
Country: China
ProdList: 3987
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Less

View Lastest Price from 1-BENZYLPYRROLIDIN-3-YL-METHANOL manufacturers

Career Henan Chemical Co

Product: 1-BENZYLPYRROLIDIN-3-YL-METHANOL 5731-17-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-25

Career Henan Chemical Co

Product: 1-BENZYLPYRROLIDIN-3-YL-METHANOL 5731-17-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 100kg
Release date: 2018-12-25

5731-17-9, 1-BENZYLPYRROLIDIN-3-YL-METHANOLRelated Search:

Octazamide 3-Hydroxymethylpyrrolidine 1-BENZYLPYRROLE 1-(4-METHYL-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID Methyl 1-Benzyl-5-oxopyrrolidine-3-carboxylate 1-(4-FLUOROBENZYL)-5-OXO-3-PYRROLIDINECARBOXYLIC ACID 1-(4-CHLOROBENZYL)-5-OXOPYRROLIDINE-3-CARBOXYLIC ACID Ethyl 1-(4-methoxybenzoyl)-2-oxo-4-phenyl-3-pyrrolidinecarboxylate 5-OXO-1-(1-PHENYL-ETHYL)-PYRROLIDINE-3-CARBOXYLIC ACID 5-OXO-1-[4-(TRIFLUOROMETHYL)BENZYL]PYRROLIDINE-3-CARBOXYLIC ACID (1'R, 3R)-1-(1'-PHENYLETHYL)-5-OXO-3-PYRROLIDINE CARBOXYLIC ACID 1-(2-METHOXY-BENZYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID 1-(2-CHLOROBENZYL)-5-OXOPYRROLIDINE-3-CARBOXYLIC ACID 1-BENZYL-2-(4-METHOXY-PHENYL)-5-OXO-PYRROLIDINE-3-CARBOXYLIC ACID 1-BENZYL-5-OXO-3-PYRROLIDINECARBOXYLIC ACID 4-BENZYL-10-OXA-4-AZATRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE 1-BENZYL-(2R,4R)-4-AMINO-PYRROLIDINE-2,4-DICARBOXYLIC ACID HCL 1-BENZYL-5-OXO-2-PHENYL-PYRROLIDINE-3-CARBOXYLIC ACID

1-BENZYL-3-HYDROXYMETHYLPYRROLIDINE

1-BENZYL-3-PYRROLIDIN-3-YLMETHANOL

CHEMBRDG-BB 4003810

3-Pyrrolidinemethanol, 1-(phenylmethyl)-

3-HYDROXYMETHYL-N-BENZYL- PYRROLIDINE

1-BENZYL-DL-BETA-PROLINOL

1-Benzyl-3-pyrrolidinemethanol

1-(Phenylmethyl)-3-pyrrolidinemethanol

(1-benzylpyrrolidin-3-yl)methanol(SALTDATA: FREE)

1-Benzylpyrrolidine-3-methanol

(1-Benzyl-1H-pyrrolidin-3-yl)Methanol

1-Benzyl-1H-pyrrolidin-3-yl-Methanol

1-Benzyl-3-hydroxyMethyl-1H-pyrrolidine

(1-Benzylpyrrolidin-3-yl)methanol hydrochloride

1-benzyl-DL-beta-prolinol, CAS 5731-17-9

5731-17-9

API intermediates

pharmacetical

Pyrrole&Pyrrolidine&Pyrroline