(GLY14)-HUMANIN (HUMAN)

Product Name: (GLY14)-HUMANIN (HUMAN)
CAS No.: 330936-70-4
Chemical Name: (GLY14)-HUMANIN (HUMAN)
Synonyms: HNG;MAPRGFSCLLLLTGEIDLPVKRRA;SHNG;[GLY14]-HN;[GLY14]-HUMANIN;[Gly14]Humanin (1);[Gly14]-Humanin G human;MAPGSGCLLLLTGEIDLPVKRRA;(GLY14)-HUMANIN (HUMAN);(Gly??)-Humanin (human)
CBNumber: CB2195681
Molecular Formula: C118H202N34O31S2
Formula Weight: 2657.21
MOL File: 330936-70-4.mol

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(GLY14)-HUMANIN (HUMAN) Property

storage temp.: −70°C
form: solid
color: White to off-white
biological source: human
Water Solubility: water: 1.00-1.04mg/mL, clear, colorless
InChIKey: WUYRHUFIUFJVQU-LIRFXKSTNA-N

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb364086
Product name: [Gly14]-Humanin
Purity: > 95%
Packaging: 1mg
Price: $552.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364086
Product name: [Gly14]-Humanin
Purity: > 95%
Packaging: 5mg
Price: $1174.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb364086
Product name: [Gly14]-Humanin
Purity: > 95%
Packaging: 10mg
Price: $1756.1
Updated: 2021/12/16

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(GLY14)-HUMANIN (HUMAN) Chemical Properties,Usage,Production

Uses

[Gly14]-Humanin G human has been used:

along with bortezomib in pharmacological inhibition studies to tre at mice to limit the toxic effects of bortezomib
to study its effect on high glucose (HG)-induced apoptosis of endothelial cells (ECs)
to study its neuroprotective effects in an in vitro oxygen-glucose deprivation/reoxygenation (OGD/R) model using SH-SY5Y neuroblastoma cells

', '[Gly1?]-Humanin G human has been used to limit the toxicity during the bortezomib treatment in neonatal brachial plexus injury (NBPI) mice model. It has also been used in the cell culture of the human-derived neuroblastoma cell line.

Biological Activity

Endogenous rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimerμs disease genes and Aβ', '[Gly14]-humanin (HNG) stimulates cell growth, proliferation, and cell cycle progression. It enhances proteins such as kinases, transporters, transmembrane receptors, and transcription and translational regulators. HNG exhibits intense in vitro neuroprotective effects compared to natural HN. Studies show th at it is an effective cytoprotectant both in vitro and in vivo. HNG is found to prevent high glucose (HG)-induced apoptosis of endothelial cells (ECs). It is proven to inhibit AngII-induced phenotypic switch in vascular smooth muscle cells (VSMCs).

in vivo

(Gly14)-Humanin (human) (0.1 μg/5 μL; i.c.v.; once) decreases cells with plasmalemma permeability in the injured cortex and hippocampus, reduces brain lesion volume, improves motor performance and ameliorates performance in the Morris water maze test^[2].

Animal Model:	Adult male CD-1 mice (25-30 g; 10-12-week-old) bearing traumatic brain injury (TBI)^[2]
Dosage:	0.1 μg/5 μL
Administration:	Intracerebroventricularly (i.c.v.); once
Result:	Decreased cells with plasmalemma permeability in the injured cortex and hippocampus, reduced brain lesion volume, improved motor performance.

(GLY14)-HUMANIN (HUMAN) Preparation Products And Raw materials

Raw materials

Preparation Products

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(GLY14)-HUMANIN (HUMAN) Suppliers

China 67 France 1 Japan 2 Switzerland 1 The Netherlands 1 United States 6 Global 78

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 970
Advantage: 59

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1010
Advantage: 55

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Adachibio Inc.

Tel: +81-8027837258; +8108027837258
Fax: 0081-80278372055
Email: sales@adachibio.com
Country: Japan
ProdList: 992
Advantage: 58

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View Lastest Price from (GLY14)-HUMANIN (HUMAN) manufacturers

Career Henan Chemical Co

Product: (GLY14)-HUMANIN (HUMAN) 330936-70-4
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

330936-70-4, (GLY14)-HUMANIN (HUMAN)Related Search:

BIOTIN-LC-EPQ-PY-EEIPIYL AC-ASP-TYR(PO3H2)-VAL-PRO-MET-LEU-NH2 BIOTIN-LC-PTYR-GLU-GLU-ILE-OH EPQ-PY-EEIPIYL* AC-PTYR-PTYR-PTYR-ILE-GLU-OH GLY-PHE-SER L-Leu-Leu-Leu [125I]-HUMANIN (HUMAN) HUMANIN TRIFLUOROACETATE (GLY14)-HUMANIN (HUMAN)

MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA

MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA TRIFLUOROACETATE

MAPRGFSCLLLLTGEIDLPVKRRA

H-MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA-OH

MAPGSGCLLLLTGEIDLPVKRRA

[GLY14]-HN

[GLY14]-HUMANIN

[GLY14] HUMANIN G (HNG), HUMAN

(GLY14)-HUMANIN (HUMAN)

[GLY14]-HUMANIN TRIFLUOROACETATE

[Gly14]-Humanin G human

HNG

SHNG

[Gly14]Humanin (1)

MET-ALA-PRO-ARG-GLY-PHE-SER-CYS-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-VAL-LYS-ARG-ARG-ALA: MAPRGFSCLLLLTGEIDLPVKRRA

sHNG, [Gly14] - HN, [Gly14] – Humanin

L-Alanine, L-methionyl-L-alanyl-L-prolyl-L-arginylglycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-

GLY14-Humanin(human) acetate

Humanin-G(human) acetate

(Gly??)-Humanin (human)

Humanin S14G, sHNG - 1 mg

(Gly14)-Humanin (human) trifluoroacetate salt

330936-70-4

C118H202N34O31S2

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