ChemicalBook > CAS DataBase List > (GLY14)-HUMANIN (HUMAN)
(GLY14)-HUMANIN (HUMAN)
- Product Name
- (GLY14)-HUMANIN (HUMAN)
- CAS No.
- 330936-70-4
- Chemical Name
- (GLY14)-HUMANIN (HUMAN)
- Synonyms
- HNG;MAPRGFSCLLLLTGEIDLPVKRRA;SHNG;[GLY14]-HN;[GLY14]-HUMANIN;[Gly14]Humanin (1);[Gly14]-Humanin G human;MAPGSGCLLLLTGEIDLPVKRRA;(GLY14)-HUMANIN (HUMAN);(Gly??)-Humanin (human)
- CBNumber
- CB2195681
- Molecular Formula
- C118H202N34O31S2
- Formula Weight
- 2657.21
- MOL File
- 330936-70-4.mol
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(GLY14)-HUMANIN (HUMAN) Property
- storage temp.
- −70°C
- form
- solid
- color
- White to off-white
- biological source
- human
- Water Solubility
- water: 1.00-1.04mg/mL, clear, colorless
- InChIKey
- WUYRHUFIUFJVQU-LIRFXKSTNA-N
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb364086
- Product name
- [Gly14]-Humanin
- Purity
- > 95%
- Packaging
- 1mg
- Price
- $552.5
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb364086
- Product name
- [Gly14]-Humanin
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $1174.7
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb364086
- Product name
- [Gly14]-Humanin
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $1756.1
- Updated
- 2021/12/16
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(GLY14)-HUMANIN (HUMAN) Chemical Properties,Usage,Production
Uses
[Gly14]-Humanin G human has been used:
- along with bortezomib in pharmacological inhibition studies to tre at mice to limit the toxic effects of bortezomib
- to study its effect on high glucose (HG)-induced apoptosis of endothelial cells (ECs)
- to study its neuroprotective effects in an in vitro oxygen-glucose deprivation/reoxygenation (OGD/R) model using SH-SY5Y neuroblastoma cells
Biological Activity
Endogenous rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimerμs disease genes and Aβ', '[Gly14]-humanin (HNG) stimulates cell growth, proliferation, and cell cycle progression. It enhances proteins such as kinases, transporters, transmembrane receptors, and transcription and translational regulators. HNG exhibits intense in vitro neuroprotective effects compared to natural HN. Studies show th at it is an effective cytoprotectant both in vitro and in vivo. HNG is found to prevent high glucose (HG)-induced apoptosis of endothelial cells (ECs). It is proven to inhibit AngII-induced phenotypic switch in vascular smooth muscle cells (VSMCs).
(GLY14)-HUMANIN (HUMAN) Preparation Products And Raw materials
Raw materials
Preparation Products
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(GLY14)-HUMANIN (HUMAN) Suppliers
- Tel
- 512-58900862 400-0707518
- Fax
- 0086-512-56765862
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- Country
- China
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- 21-61263452 13641803416
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- 86-21-61263399
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- 021-54306202 13764082696
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- China
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- 021-50135380
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- China
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- 0086-411-39042693
- sales@alphabiopharm.com
- Country
- China
- ProdList
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View Lastest Price from (GLY14)-HUMANIN (HUMAN) manufacturers
Career Henan Chemical Co
- Product
- (GLY14)-HUMANIN (HUMAN) 330936-70-4
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16
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